2-(4-氯苯基)-alpha-甲基-5-苯并恶唑乙酸乙酯合成路线 （共 11 条）
反应条件
sodium hydroxide in ethanol 4.5 h; Heating;
参考文献
Dunwell,D.W. et al.
Journal of Medicinal Chemistry, 1975 , vol. 18, # 1 p. 53 - 58
反应条件
1: HNO3 / acetic acid
2: SnCl2, aq. HCl / ethanol
3: Py
4: aq. HCl / 2.5 h / Heating
5: TsOH / benzene / 12 h / Heating
View Scheme
参考文献
Dunwell,D.W. et al.
Journal of Medicinal Chemistry, 1975 , vol. 18, # 1 p. 53 - 58
反应条件
1: SnCl2, aq. HCl / ethanol
2: Py
3: aq. HCl / 2.5 h / Heating
4: TsOH / benzene / 12 h / Heating
View Scheme
参考文献
Dunwell,D.W. et al.
Journal of Medicinal Chemistry, 1975 , vol. 18, # 1 p. 53 - 58
反应条件
1: Py
2: aq. HCl / 2.5 h / Heating
3: TsOH / benzene / 12 h / Heating
View Scheme
参考文献
Dunwell,D.W. et al.
Journal of Medicinal Chemistry, 1975 , vol. 18, # 1 p. 53 - 58
反应条件
1: (i) NaNO2, aq. HCl, (ii) aq. H2SO4
2: HNO3 / acetic acid
3: SnCl2, aq. HCl / ethanol
4: Py
5: aq. HCl / 2.5 h / Heating
6: TsOH / benzene / 12 h / Heating
View Scheme
参考文献
Dunwell,D.W. et al.
Journal of Medicinal Chemistry, 1975 , vol. 18, # 1 p. 53 - 58
反应条件
1: Py
2: TsOH / benzene / 12 h / Heating
View Scheme
参考文献
Dunwell,D.W. et al.
Journal of Medicinal Chemistry, 1975 , vol. 18, # 1 p. 53 - 58
反应条件
1: Py
2: TsOH / benzene / 12 h / Heating
View Scheme
参考文献
Dunwell,D.W. et al.
Journal of Medicinal Chemistry, 1975 , vol. 18, # 1 p. 53 - 58
反应条件
1: aq. HCl / 2.5 h / Heating
2: TsOH / benzene / 12 h / Heating
View Scheme
参考文献
Dunwell,D.W. et al.
Journal of Medicinal Chemistry, 1975 , vol. 18, # 1 p. 53 - 58
反应条件
toluene-4-sulfonic acid in benzene
12 h; Heating;
参考文献
Dunwell,D.W. et al.
Journal of Medicinal Chemistry, 1975 , vol. 18, # 1 p. 53 - 58
参考文献
Dunwell,D.W. et al.
Journal of Medicinal Chemistry, 1975 , vol. 18, # 1 p. 53 - 58
