(S)-(+)-2-苄氨基-1-苯乙醇合成路线 (共 33 条)
反应条件
1: Et3N / CH2Cl2 / 3 h 2: 0.98 g / NaBH4 / aq. methanol View Scheme
参考文献
Kawamoto; Wills
Journal of the Chemical Society. Perkin Transactions 1, 2001 , # 16 p. 1916 - 1928
反应条件
1: Et3N / CH2Cl2 / 3 h 2: 0.98 g / NaBH4 / aq. methanol View Scheme
参考文献
Nielsen, Dennis U.; Neumann, Karoline; Taaning, Rolf H.; Lindhardt, Anders T.; Modvig, Amalie; Skrydstrup, Troels
Journal of Organic Chemistry, 2012 , vol. 77, # 14 p. 6155 - 6165
反应条件
1: benzene / 0.08 h / Ambient temperature 2: 56 percent / NaBH4 / methanol / 0.5 h / Ambient temperature View Scheme
参考文献
Alcaide, Benito; Escobar, Gerardo; Perez-Ossorio, Rafael; Plumet, Joaquin; Sanz, Dionisia
Journal of Chemical Research, Miniprint, 1984 , # 5 p. 1466 - 1488
反应条件
1.1: tri-tert-butyl phosphine; N,N-dicyclohexylmethylamine; bis(dibenzylideneacetone)-palladium(0) / N,N-dimethyl-formamide / Inert atmosphere 1.2: 20 °C / Inert atmosphere 2.1: sodium tetrahydroborate; iodine / tetrahydrofuran / 16 h / 60 °C / Inert atmosphere 2.2: Inert atmosphere View Scheme
参考文献
Nielsen, Dennis U.; Neumann, Karoline; Taaning, Rolf H.; Lindhardt, Anders T.; Modvig, Amalie; Skrydstrup, Troels
Journal of Organic Chemistry, 2012 , vol. 77, # 14 p. 6155 - 6165
反应条件
ethanol; platinum Hydrogenation;
参考文献
Gruber; Renner
Monatshefte fuer Chemie, 1950 , vol. 81, p. 751,758
反应条件
in diethyl ether 2 h; Ambient temperature; Yield given. Yields of byproduct given;
参考文献
Yamada, Jun-ichi; Yumoto, Masatoshi; Yamamoto, Yoshinori
Tetrahedron Letters, 1989 , vol. 30, # 32 p. 4255 - 4258
参考文献
UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL
Patent: WO2005/12209 A2, 2005 ;
Location in patent: Page/Page column 60 ;
反应条件
(i), (ii) KBH4; Multistep reaction;
参考文献
Jeffs,P.W. et al.
Journal of Organic Chemistry, 1975 , vol. 40, p. 2883 - 2890
参考文献
Srinivasan; Gupta; Kundu
Tetrahedron Letters, 2001 , vol. 42, # 34 p. 5993 - 5995
参考文献
Fischer,E.
Chemische Berichte, 1896 , vol. 29, p. 207