2-溴-1-O-甲苯基-乙酮合成路线 （共 13 条）
反应条件
hydrogen bromide in hexane; water; ethyl acetate; acetonitrile
参考文献
CHIESI FARMACEUTICI S.p.A.; AMARI, Gabriele; RICCABONI, Mauro; BOSSOLO, Stefano
Patent: WO2011/161018 A1, 2011 ;
Location in patent: Page/Page column 35 ;
WO 2011/161018 A1
反应条件
N-bromosuccinmide; silica gel in methanol 0.283333 h; Reflux; chemoselective reaction;
参考文献
Mohan Reddy, Bodireddy; Venkata Ramana Kumar, Velpula; Chinna Gangi Reddy, Nallagondu; Mahender Rao, Siripragada
Chinese Chemical Letters, 2014 , vol. 25, # 1 p. 179 - 182
反应条件
Oxonereg;; NH4Br in methanol T=20°C; 26 h; regioselective reaction;
参考文献
Mohan, Reddy Bodireddy; Reddy, N. C. Gangi
Synthetic Communications, 2013 , vol. 43, # 19 p. 2603 - 2614
反应条件
pyridinium hydrobromide perbromide in tetrahydrofuran; chloroform
参考文献
Japan Tobacco Inc.
Patent: EP885869 A1, 1998 ;
反应条件
hydrogen bromide; oxygen in water; ethyl acetate 5 h; Irradiation;
参考文献
Nobuta, Tomoya; Hirashima, Shin-Ichi; Tada, Norihiro; Miura, Tsuyoshi; Itoh, Akichika
Synlett, 2010 , # 15 p. 2335 - 2339
反应条件
1: diethyl ether / Behandeln des in Aethanol geloesten Reaktionsprodukts mit wss. NaOH 2: bromine View Scheme
参考文献
Baker
Journal of the Chemical Society, 1938 , p. 445,447
参考文献
Mayer; Freund
Chemische Berichte, 1922 , vol. 55, p. 2056
Full Text Show Details
Borsche; Herbert
Justus Liebigs Annalen der Chemie, 1941 , vol. 546, p. 277,291
参考文献
Mayer; Freund
Chemische Berichte, 1922 , vol. 55, p. 2056
Full Text Show Details
Borsche; Herbert
Justus Liebigs Annalen der Chemie, 1941 , vol. 546, p. 277,291
反应条件
in ethanol; water T=20°C;
参考文献
Lee, Sunkyung; Kim, Taemi; Lee, Byung Ho; Yoo, Sung-eun; Lee, Kyunghee; Yi, Kyu Yang
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 5 p. 1291 - 1295
反应条件
water T=125°C; 0.416667 h; microwave irradiation;
参考文献
Utsukihara, Takamitsu; Nakamura, Hiroaki; Watanabe, Masashige; Akira Horiuchi
Tetrahedron Letters, 2006 , vol. 47, # 52 p. 9359 - 9364
