1: isopropyl bromide With iodine; magnesium in tetrahydrofuran Heating; 2: 6-bromohexanoic acid sodium salt With dilithium tetrachlorocuprate in tetrahydrofuran T=-10°C; 4 h; 3: With lithium aluminium tetrahydride in tetrahydrofuran 1 h; Heating;
参考文献
Klimentova, Jana; Kosak, Petr; Vavrova, Katerina; Holas, Tomas; Hrabalek, Alexandr
Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 23 p. 7681 - 7687
1: 1-bromo-4-methyl-pentane With iodine; magnesium in tetrahydrofuran
Heating;
2: 6-bromohexanoic acid sodium salt With dilithium tetrachlorocuprate in tetrahydrofuran
T=-10°C; 4 h;
3: With lithium aluminium tetrahydride in tetrahydrofuran
1 h; Heating;
参考文献
Klimentova, Jana; Kosak, Petr; Vavrova, Katerina; Holas, Tomas; Hrabalek, Alexandr
Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 23 p. 7681 - 7687
1: 2-methyl-1-bromopropane With iodine; magnesium in tetrahydrofuran
Heating;
2: 6-bromohexanoic acid sodium salt With dilithium tetrachlorocuprate in tetrahydrofuran
T=-10°C; 4 h;
3: With lithium aluminium tetrahydride in tetrahydrofuran
1 h; Heating;
参考文献
Klimentova, Jana; Kosak, Petr; Vavrova, Katerina; Holas, Tomas; Hrabalek, Alexandr
Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 23 p. 7681 - 7687
1: 1-bromo-3-methyl-butane With iodine; magnesium in tetrahydrofuran
Heating;
2: 6-bromohexanoic acid sodium salt With dilithium tetrachlorocuprate in tetrahydrofuran
T=-10°C; 4 h;
3: With lithium aluminium tetrahydride in tetrahydrofuran
1 h; Heating;
参考文献
Klimentova, Jana; Kosak, Petr; Vavrova, Katerina; Holas, Tomas; Hrabalek, Alexandr
Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 23 p. 7681 - 7687
