2,3,4,5-四氢吡啶合成路线 （共 43 条）
反应条件
lithium 1.) Ether, reflux, 2.) RT, 30 min; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Scully, Frank E.
Journal of Organic Chemistry, 1980 , vol. 45, # 8 p. 1515 - 1517
反应条件
1: N-bromosuccinmide; sodium hydroxide / water / 0.33 h / 45 °C / pH 1.9 / Inert atmosphere 2: hydrogenchloride / water / 3 h / 20 °C / pH 1.9 - 3 / Inert atmosphere View Scheme
参考文献
Rouchaud, Anne; Braekman, Jean-Claude
European Journal of Organic Chemistry, 2011 , # 12 p. 2346 - 2353
反应条件
acetic acid Inert atmosphere;
参考文献
Orejarena Pacheco, Julio Cesar; Lahm, Guenther; Opatz, Till
Journal of Organic Chemistry, 2013 , vol. 78, # 10 p. 4985 - 4992
反应条件
aqueous solution of pH 11.5
参考文献
Schoepf et al.
Justus Liebigs Annalen der Chemie, 1970 , vol. 737, p. 1,14, 16
Angewandte Chemie, 1953 , vol. 65, p. 161
Full Text Show Details
Schoepf et al.
Angewandte Chemie, 1953 , vol. 65, p. 161
Justus Liebigs Annalen der Chemie, 1970 , vol. 737, p. 1,2 Anm. 5
参考文献
Schoepf et al.
Justus Liebigs Annalen der Chemie, 1970 , vol. 737, p. 1,14, 16
Angewandte Chemie, 1953 , vol. 65, p. 161
Full Text Show Details
Schoepf et al.
Angewandte Chemie, 1953 , vol. 65, p. 161
Justus Liebigs Annalen der Chemie, 1970 , vol. 737, p. 1,2 Anm. 5
反应条件
in dichloromethane Yield given;
参考文献
Castro, C. E.; Jamin, Mary; Yokoyama, W.; Wade, Ruth
Journal of the American Chemical Society, 1986 , vol. 108, # 14 p. 4179 - 4187
反应条件
in dichloromethane T=20°C; Betti reaction; regioselective reaction;
参考文献
Cimarelli, Cristina; Fratoni, Davide; Mazzanti, Andrea; Palmieri, Gianni
European Journal of Organic Chemistry, 2011 , # 11 p. 2094 - 2100
反应条件
tert.-butyl lithium 1.) ether, -120 deg C, 0.5 h, 2.) -100 deg C to -40 deg C, 2.5 h; Yield given. Multistep reaction;
参考文献
Scully, Frank E.
Journal of Organic Chemistry, 1980 , vol. 45, # 8 p. 1515 - 1517
反应条件
chloroiron(III) mesoporphyrin IX dimethyl ester in dichloromethane
3 h;
参考文献
Castro, C. E.; Jamin, Mary; Yokoyama, W.; Wade, Ruth
Journal of the American Chemical Society, 1986 , vol. 108, # 14 p. 4179 - 4187
反应条件
[BnEt3N]2MoS4 in water; acetonitrile
T=25°C; 8 h;
参考文献
Ramesha, A. R.; Bhat, Shridhar; Chandrasekaran, Srinivasan
Journal of Organic Chemistry, 1995 , vol. 60, # 23 p. 7682 - 7683
