1: 84 percent / anh. potassium carbonate / acetone / 34 h / Heating 2: 20 percent / sodium ethoxide / ethanol / 0.5 h / Heating 3: 92 percent / sulfuric acid / 4 h / Heating 4: 91 percent / ammonia / ethanol / 48 h / 120 °C 5: 90 percent / anh. potassium carbonate / acetone / 15 h / Heating 6: 91 percent / pyridine, trifluoroacetic anhydride / CH2Cl2 / Ambient temperature View Scheme

1: 84 percent / anh. potassium carbonate / acetone / 34 h / Heating 2: 20 percent / sodium ethoxide / ethanol / 0.5 h / Heating 3: 92 percent / sulfuric acid / 4 h / Heating 4: 70 percent / p-toluenesulfonic acid monohydrate / toluene / 9 h / Heating 5: 81 percent / hydrogen / 10percent Pd/C / acetic acid / 12 h / 2844.3 Torr / Ambient temperature 6: 88 percent / phosphoryl chloride / 1 h / 120 °C 7: 80 percent / sodium methoxide / methanol / 5 h / Heating 8: 50 percent / lithium aluminum hydride / tetrahydrofuran / 22 h / 0 °C View Scheme

zinc(II) chloride T=180°C;

toluene-4-sulfonic acid in benzene T=59 - 79°C; Etherification;

Multi-step reaction with 2 steps 1: p-toluenesulfonic acid monohydrate / benzene / 59 - 79 °C2: 84 percent / Et3N / diethyl ether / 3 h / 0 °C  

Multi-step reaction with 3 steps 1: 84 percent / anh. potassium carbonate / acetone / 34 h / Heating2: 20 percent / sodium ethoxide / ethanol / 0.5 h / Heating3: 92 percent / sulfuric acid / 4 h / Heating  

Multi-step reaction with 6 steps 1: 84 percent / anh. potassium carbonate / acetone / 34 h / Heating2: 20 percent / sodium ethoxide / ethanol / 0.5 h / Heating3: 92 percent / sulfuric acid / 4 h / Heating4: 70 percent / p-toluenesulfonic acid monohydrate / toluene / 9 h / Heating5: 81 percent / hydrogen / 10percent Pd/C / acetic acid / 12 h / 2844.3 Torr / Ambient temperature6: 88 percent / phosphoryl chloride / 1 h / 120 °C  

With  diethyl ether; sodium ethanolate  ueber mehrere Stufen das Natriumsalz entsteht;