2-(3-甲氧基苯基)乙醇合成路线 （共 48 条）
反应条件
borane in tetrahydrofuran 2 h; Ambient temperature;
参考文献
Parker, Kathlyn A.; Fokas, Demosthenes
Journal of Organic Chemistry, 1994 , vol. 59, # 14 p. 3933 - 3938
反应条件
1: 3-methoxybromobenzene With n-butyllithium in tetrahydrofuran; hexane T=-78°C; 2.5 h; 2: ethylene glycol cyclic sulfate in tetrahydrofuran; hexane T=20°C; 16 h; 3: With sulfuric acid in tetrahydrofuran; hexane 47 h; Heating; Further stages.;
参考文献
Schlaeger, Torsten; Oberdorf, Christoph; Tewes, Bastian; Wuensch, Bernhard
Synthesis, 2008 , # 11 p. 1793 - 1797
反应条件
lithium aluminium tetrahydride in tetrahydrofuran T=25°C; 22 h;
参考文献
Ponton, John; Helquist, Paul; Conrad, Preston C.; Fuchs, Philip L.
Journal of Organic Chemistry, 1981 , vol. 46, # 1 p. 118 - 122
反应条件
hydrogenchloride in tetrahydrofuran; methanol
参考文献
ELI LILLY AND COMPANY
Patent: EP838459 A1, 1998 ;
反应条件
4,4'-di-tert-butylbiphenyl; lithium in tetrahydrofuran T=-40°C; Wittig rearrangement; 1 h;
参考文献
Gomez, Cecilia; Macia, Beatriz; Lillo, Victor J.; Yus, Miguel
Tetrahedron, 2006 , vol. 62, # 42 p. 9832 - 9839
反应条件
n-butyllithium 1) THF, Et2O, -78 deg C, 1 h 40 min, rt, overnight; Yield givenMultistep reaction;
参考文献
Luo, Shuang; Yu, Da-Gang; Zhu, Ru-Yi; Wang, Xin; Wang, Lei; Shi, Zhang-Jie
Chemical Communications, 2013 , vol. 49, # 71 p. 7794 - 7796
参考文献
Rapson; Robinson
Journal of the Chemical Society, 1935 , p. 1533,1543
Full Text Show Details
Hunter; Hogg
Journal of the American Chemical Society, 1949 , vol. 71, p. 1922,1924
反应条件
diethyl ether; benzene
参考文献
Bachmann; Thomas
Journal of the American Chemical Society, 1942 , vol. 64, p. 94,95
反应条件
1: 78 percent / sodium iodide; sodium hydride / tetrahydrofuran / 0 - 20 °C 2: sulfuryl chloride / CH2Cl2 / -78 °C 3: 52 percent / lithium; 4,4'-di-tert-butylbiphenyl / tetrahydrofuran / 1 h / -40 °C View Scheme
参考文献
Rapson; Robinson
Journal of the Chemical Society, 1935 , p. 1533,1543
反应条件
1: With 4-bromooctafluorobutanetriethoxysilane; H2O*Rh(2+)*2C2H3O2(1-)*C18H24N2O2 in toluene T=30°C; 1 h; 2: With potassium fluoride; dihydrogen peroxide; potassium hydrogencarbonate in tetrahydrofuran; methanol enantioselective reaction;
参考文献
Naito, Tatsuo; Yoneda, Takuma; Ito, Jun-Ichi; Nishiyama, Hisao
Synlett, 2012 , vol. 23, # 20 p. 2957 - 2960
