Yield given. Multistep reaction;

1.1: iodine; potassium hydroxide / -5 - 0 °C 2.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 24 h / 20 °C 3.1: methanol; water; sodium hydroxide / 5 h / Reflux 3.2: 1 h / Reflux 4.1: iodine; potassium hydroxide / -5 - 0 °C 5.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 24 h / 20 °C 6.1: methanol; water; sodium hydroxide / 5 h / Reflux 6.2: 1 h / Reflux 7.1: iodine; potassium hydroxide / -5 - 0 °C 8.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 24 h / 20 °C 9.1: methanol; water; sodium hydroxide / 5 h / Reflux 9.2: 1 h / Reflux 10.1: potassium tert-butylate / tert-butyl alcohol / 50 °C View Scheme

1.1: bromine / toluene; diethyl ether / 0.5 h / 20 - 25 °C 1.2: 97 percent / toluene / 0.5 h / 20 - 25 °C 2.1: 69 percent / sulfuric acid; sodium azide / CHCl3 / 5 - 40 °C View Scheme

1.1: iodine; potassium hydroxide / -5 - 0 °C 2.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 24 h / 20 °C 3.1: methanol; water; sodium hydroxide / 5 h / Reflux 3.2: 1 h / Reflux 4.1: iodine; potassium hydroxide / -5 - 0 °C 5.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 24 h / 20 °C 6.1: methanol; water; sodium hydroxide / 5 h / Reflux 6.2: 1 h / Reflux 7.1: iodine; potassium hydroxide / -5 - 0 °C 8.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 24 h / 20 °C 9.1: methanol; water; sodium hydroxide / 5 h / Reflux 9.2: 1 h / Reflux 10.1: iodine; potassium hydroxide / -5 - 0 °C 11.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 24 h / 20 °C 12.1: methanol; water; sodium hydroxide / 5 h / Reflux 12.2: 1 h / Reflux 13.1: iodine; potassium hydroxide / -5 - 0 °C 14.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 24 h / 20 °C 15.1: methanol; water; sodium hydroxide / 5 h / Reflux 15.2: 1 h / Reflux View Scheme

chromium(VI) oxide; acetic acid

暂无反应条件数据

暂无反应条件数据

1: NH2OH*HCl 2: 89 percent / aq. H2O2; HCl / CH2Cl2 / 0.33 h / 38 - 40 °C View Scheme

1.1: CeCl3 / tetrahydrofuran / 0.5 h / 20 °C 1.2: tetrahydrofuran / 0.5 h / 25 °C 2.1: 650 °C / 0.75 - 3 Torr View Scheme

lithium diisopropyl amide 1) THF, -78 deg C, 30 min; 2) 1 h at -78 deg C to room temp.; Yield given. Multistep reaction;