(4,5-二苯基-4H-[1,2,4]噻唑-3-磺酰基)-乙酸肼合成路线 （共 5 条）
反应条件
hydrazine hydrate in ethanol T=20°C; 24 h;
参考文献
Popiolek, Lukasz; Kosikowska, Urszula; Mazur, Liliana; Dobosz, Maria; Malm, Anna
Medicinal Chemistry Research, 2013 , vol. 22, # 7 p. 3134 - 3147
反应条件
1: 75 percent / K2CO3 / acetone / 4 h / Heating 2: 76 percent / hydrazine hydrate / ethanol / 3 h / Heating View Scheme
参考文献
Popiolek, Lukasz; Kosikowska, Urszula; Mazur, Liliana; Dobosz, Maria; Malm, Anna
Medicinal Chemistry Research, 2013 , vol. 22, # 7 p. 3134 - 3147
反应条件
1: aq. NaOH / Heating 2: 75 percent / K2CO3 / acetone / 4 h / Heating 3: 76 percent / hydrazine hydrate / ethanol / 3 h / Heating View Scheme
参考文献
Ismaiel, A. M.; Yousif, M. Y.; Metwally, M. A.; El-Kerdawy, M. M.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1984 , vol. 23, # 5 p. 489 - 491
反应条件
1: aq. NaOH / Heating 2: 75 percent / K2CO3 / acetone / 4 h / Heating 3: 76 percent / hydrazine hydrate / ethanol / 3 h / Heating View Scheme
参考文献
Ismaiel, A. M.; Yousif, M. Y.; Metwally, M. A.; El-Kerdawy, M. M.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1984 , vol. 23, # 5 p. 489 - 491
反应条件
1: |Alkaline conditions 2: sodium ethanolate / ethanol / 17 h / 20 °C / |Heating 3: hydrazine hydrate / ethanol / 24 h / 20 °C View Scheme
参考文献
Popiolek, Lukasz; Kosikowska, Urszula; Mazur, Liliana; Dobosz, Maria; Malm, Anna
Medicinal Chemistry Research, 2013 , vol. 22, # 7 p. 3134 - 3147
