(3-氨基-1-苯并呋喃-2-基)(苯基)甲酮合成路线 （共 12 条）
反应条件
hydrazine hydrate in 2-methoxy-ethanol 12 h; Heating; Yield given;
参考文献
Gatta; Settimj
Journal of Heterocyclic Chemistry, 1984 , vol. 21, # 4 p. 937 - 943
反应条件
hydrazine hydrate in 2-methoxy-ethanol 12 h; Heating; Yield given;
参考文献
Gatta; Settimj
Journal of Heterocyclic Chemistry, 1984 , vol. 21, # 4 p. 937 - 943
反应条件
1: 76 percent / pyridine / 24 h / refrigerator 2: 17 percent / hydrazine hydrate (98 percent) / ethanol / 2.5 h / Heating 3: 99 percent / hydrochloric acid (conc.) / ethanol; H2O / 2 h / Heating View Scheme
参考文献
Gatta; Settimj
Journal of Heterocyclic Chemistry, 1984 , vol. 21, # 4 p. 937 - 943
反应条件
potassium carbonate in acetone
T=60°C; 18 h; Inert atmosphere;
参考文献
Crowe, Miriam; Daugan, Alain Claude-Marie; Gosmini, Romain Luc Marie; Grimes, Richard Martin; Mirguet, Olivier; Mordaunt, Jacqueline Elizabeth
Patent: US2012/202799 A1, 2012 ;
Location in patent: Page/Page column 44-45 ;
反应条件
sodium methylate in methanol
T=20°C; Cyclization; 0.5 h;
参考文献
Radl, Stanislav; Hezky, Petr; Urbankova, Jitka; Vachal, Petr; Krejci, Ivan
Collection of Czechoslovak Chemical Communications, 2000 , vol. 65, # 2 p. 280 - 296
反应条件
1: 83 percent / NaOH; H2O / 2-methoxy-ethanol / 0.25 h / Heating
2: 89 percent / NaOMe / methanol / 0.5 h / 20 °C
View Scheme
参考文献
Radl, Stanislav; Hezky, Petr; Urbankova, Jitka; Vachal, Petr; Krejci, Ivan
Collection of Czechoslovak Chemical Communications, 2000 , vol. 65, # 2 p. 280 - 296
反应条件
1: 83 percent / NaOH; H2O / 2-methoxy-ethanol / 0.25 h / Heating
2: 89 percent / NaOMe / methanol / 0.5 h / 20 °C
View Scheme
参考文献
Radl, Stanislav; Hezky, Petr; Urbankova, Jitka; Vachal, Petr; Krejci, Ivan
Collection of Czechoslovak Chemical Communications, 2000 , vol. 65, # 2 p. 280 - 296
反应条件
potassium hydroxide; hydroxylamine hydrochloride in ethanol
4 h; Heating;
参考文献
Gatta, Franco; Settimj, Guido
Journal of Heterocyclic Chemistry, 1983 , vol. 20, p. 1251 - 1254
反应条件
1: 40 percent / NH2OH.HCl, KOH / aq. ethanol / 4 h / Heating
2: 65 percent / pyridine / dioxane / 3 h / Ambient temperature
View Scheme
参考文献
Gatta, Franco; Settimj, Guido
Journal of Heterocyclic Chemistry, 1983 , vol. 20, p. 1251 - 1254
反应条件
Acylation; 2 h; Heating;
参考文献
Radl, Stanislav; Hezky, Petr; Konvicka, Petr; Krejci, Ivan
Collection of Czechoslovak Chemical Communications, 2000 , vol. 65, # 7 p. 1093 - 1108
