1-(2,4-二羟基苯基)-2-(4-甲氧基苯基)乙酮合成路线 （共 38 条）
反应条件
1: 72 percent / K2CO3 / acetone / 24 h / Heating 2: 48 percent / aq. NaOH / 2 h / 60 °C 3: 70 percent / hydrogen / Pd/C / methanol / 7 h / 2068.65 - 2585.81 Torr View Scheme
参考文献
Gupta, Atul; Ray, Suprabhat
Synthetic Communications, 2007 , vol. 37, # 18 p. 3119 - 3126
参考文献
Baker; Jukes; Subrahmanyam
Journal of the Chemical Society, 1934 , p. 1681,1683
反应条件
1: 2,4-dihydroxy-4'-methoxy deoxybenzoin With boron trifluoride diethyl etherate in N,N-dimethyl-formamide T=55°C; Inert atmosphere; 2: N,N-dimethyl-formamide With methanesulfonyl chloride T=55 - 80°C; 3 h; Inert atmosphere;
参考文献
Journal of Molecular Structure, , vol. 967, # 1-3 p. 25 - 33
反应条件
methanesulfonyl chloride in N,N-dimethyl-formamide T=60 - 70°C; 1.5 h;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 12 p. 3005 - 3008
反应条件
1: N,N-dimethyl-formamide With phosphorus pentachloride T=55°C; Chlorination; 0.333333 h; 2: 2,4-dihydroxy-4'-methoxy deoxybenzoin With boron trifluoride diethyl etherate in N,N-dimethyl-formamide T=20°C; Cycloaddition; 1 h;
参考文献
Synthetic Communications, , vol. 30, # 3 p. 469 - 484
反应条件
boron trifluoride diethyl etherate; acetic anhydride in diethyl ether; acetic acid Heating;
参考文献
Angewandte Chemie, , vol. 93, # 1 p. 129 - 130
反应条件
in tetrahydrofuran 0.0333333 h; HeatingIrradiation;
参考文献
Journal of Agricultural and Food Chemistry, , vol. 42, # 9 p. 1869 - 1871
反应条件
1: in N,N-dimethyl-formamide T=10 - 30°C; 2: With hydrogenchloride; water in N,N-dimethyl-formamide Reflux;
参考文献
Bioorganic and Medicinal Chemistry, , vol. 18, # 9 p. 3036 - 3042
反应条件
1: 2,4-dihydroxy-4'-methoxy deoxybenzoin With boron trifluoride diethyl etherate in N,N-dimethyl-formamide T=0°C; 2: methanesulfonyl chloride T=100°C; 2 h;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 2 p. 677 - 681
反应条件
piperidine; pyridine
参考文献
Journal of Scientific and Industrial Research, , vol. 15 B, p. 325
