4-甲基-2-苯基-喹啉合成路线 （共 49 条）
反应条件
ytterbium(III) triflate in acetonitrile
0.5 h; Ambient temperature;
参考文献
Makioka; Shindo; Taniguchi; Takaki; Fujiwara
Synthesis, 1995 , # 7 p. 801 - 804
反应条件
gallium(III) chloride; chloranil in dichloromethane
T=20°C; 21 h;
参考文献
Hirashita, Tsunehisa; Kawai, Daisuke; Araki, Shuki
Tetrahedron Letters, 2007 , vol. 48, # 31 p. 5421 - 5424
反应条件
potassium iodide; PdI2
T=100°C; P=45603.1 Torr; 2 h;
参考文献
Gabriele, Bartolo; Mancuso, Raffaella; Salerno, Giuseppe; Lupinacci, Elvira; Ruffolo, Giuseppe; Costa, Mirco
Journal of Organic Chemistry, 2008 , vol. 73, # 13 p. 4971 - 4977
反应条件
1.1: n-BuLi / tetrahydrofuran / 0.5 h / 0 °C
1.2: 72 percent / tetrahydrofuran / 1 h / 0 °C
2.1: 82 percent / Fe; aq. HCl / ethanol / 2 h / 80 °C
View Scheme
参考文献
Sandelier, Matthew J.; DeShong, Philip
Organic Letters, 2007 , vol. 9, # 17 p. 3209 - 3212
反应条件
air; potassium iodide; PdI2
T=100°C; P=60804.1 Torr; 2 h;
参考文献
Gabriele, Bartolo; Mancuso, Raffaella; Salerno, Giuseppe; Lupinacci, Elvira; Ruffolo, Giuseppe; Costa, Mirco
Journal of Organic Chemistry, 2008 , vol. 73, # 13 p. 4971 - 4977
反应条件
1: With N,N,N',N,-tetramethylethylenediamine in toluene
T=50°C; 10 h; Inert atmosphere;
2: With water; ammonium chloride in toluene
12 h;
参考文献
Zhuo, Fang-Fang; Xie, Wen-Wen; Yang, Yong-Xin; Zhang, Lei; Wang, Pei; Yuan, Rui; Da, Chao-Shan
Journal of Organic Chemistry, 2013 , vol. 78, # 7 p. 3243 - 3249
反应条件
in ethylene glycol dimethyl ether
T=-78°C; 0.5 h;
参考文献
Kobayashi, Kazuhiro; Yoneda, Keiichi; Miyamoto, Kazuna; Morikawa, Osamu; Konishi, Hisatoshi
Tetrahedron, 2004 , vol. 60, # 50 p. 11639 - 11645
反应条件
ytterbium(III) triflate in acetonitrile
Ambient temperature;
参考文献
Kobayashi; Ishitani; Nagayama
Synthesis, 1995 , # 9 p. 1195 - 1202
反应条件
1.1: EtMgBr / tetrahydrofuran / 2 h / 50 °C
1.2: tetrahydrofuran / 50 °C
2.1: 1.42 g / CuCl2 / methanol / 5 h / 100 °C
View Scheme
参考文献
Gabriele, Bartolo; Mancuso, Raffaella; Salerno, Giuseppe; Ruffolo, Giuseppe; Plastina, Pierluigi
Journal of Organic Chemistry, 2007 , vol. 72, # 18 p. 6873 - 6877
反应条件
boron trifluoride diethyl etherate in dichloromethane
T=20°C; Kametani reaction; 48 h;
参考文献
Kouznetsov, Vladimir V.; Melendez Gomez, Carlos M.; Urbina Gonzalez, Juan M.; Stashenko, Elena E.; Bahsas, Ali; Amaro-Luis, Juan
Journal of Heterocyclic Chemistry, 2007 , vol. 44, # 3 p. 551 - 555
