反应条件
1: 1-benzyl-2-oxo-piperidine With 2,6-di-tert-butyl-4-methylpyridine; trifluoromethylsulfonic anhydride in dichloromethane
T=-78 - 0°C; 1 h; Inert atmosphere;
2: halo(propyl)magnesium in diethyl ether; dichloromethane
T=-78 - 20°C; 1 h; Inert atmosphere;
3: With lithium aluminium tetrahydride in diethyl ether; dichloromethane
T=20°C; 1 h; Inert atmosphere;
参考文献
Xiao, Kai-Jiong; Wang, Yu; Huang, Ying-Hong; Wang, Xiao-Gang; Huang, Pei-Qiang
Journal of Organic Chemistry, 2013 , vol. 78, # 17 p. 8305 - 8311
