2,2',3,3',4',6,6'-七-O-乙酰基-alpha-D-乳糖基溴化物合成路线 （共 37 条）
反应条件
1: 1.) HgO, HgBr2, CaSO4, 2.) HgBr2 / 1.) CHCl3, 20 h, 2.) toluene, nitromethane, 50 deg C, 24 h 2: BF3*Et2O / toluene / 3 h / 22 °C View Scheme
参考文献
Jansson, Karl; Ahlfors, Stefan; Frejd, Torbjoern; Kihlberg, Jan; Magnusson, Goeran; et al.
Journal of Organic Chemistry, 1988 , vol. 53, # 24 p. 5629 - 5647
反应条件
sodium carbonate; tetra(n-butyl)ammonium hydrogensulfate in dichloromethane Ambient temperature;
参考文献
Tropper; Andersson; Grand-Maitre; Roy
Carbohydrate Research, 1992 , vol. 229, # 1 p. 149 - 154
反应条件
β-cyclodextrin; zinc in water
T=20°C; 1.5 h; Sonication;
参考文献
Zhao, Jinzhong; Shao, Huawu; Wu, Xin; Shi, Shaojing
Chinese Journal of Chemistry, 2011 , vol. 29, # 7 p. 1434 - 1440
反应条件
N(Et)4ClO4 in acetonitrile
Dimerization; elimination; Electrolysis;
参考文献
Alberti, Angelo; Bertini, Sabrina; Comoli, Maura; Guerrini, Marco; Mele, Andrea; Vismara, Elena
Tetrahedron, 2000 , vol. 56, # 34 p. 6291 - 6297
反应条件
1: With iron(III) chloride in nitromethane
T=25°C; 1 h;
2: With sodium methylate in methanol
T=20°C; Zemplen deacetylation;
参考文献
Koto, Shinkiti; Hirooka, Motoko; Tashiro, Takako; Sakashita, Motokazu; Hatachi, Masaharu; Kono, Takayuki; Shimizu, Miho; Yoshida, Nahoko; Kurasawa, Sayaka; Sakuma, Natsuko; Sawazaki, Sunao; Takeuchi, Akihiro; Shoya, Naomi; Nakamura, Emi
Carbohydrate Research, 2004 , vol. 339, # 14 p. 2415 - 2424
反应条件
1: With Ag2CO3 in dichloromethane
T=20°C; 5 h;
2: With methanol; sodium hydroxide in chloroform
参考文献
Zhao, Haisuo; Naito, Hiroyuki; Ueda, Yoshimi; Okada, Katsuhide; Sadagane, Kenji; Izumi, Minoru; Nakajima, Shuhei; Baba, Naomichi
Bioscience, Biotechnology and Biochemistry, 2008 , vol. 72, # 11 p. 3006 - 3010
反应条件
1: 84 percent / Et3N / acetonitrile / 18 h / Ambient temperature
2: 12 percent / MeONa / methanol; CH2Cl2 / 1.7 h / Ambient temperature
View Scheme
参考文献
Guilbert; Davis; Pearce; Aplin; Flitsch
Tetrahedron Asymmetry, 1994 , vol. 5, # 11 p. 2163 - 2178
