1,4-环己二酮单乙二醇缩酮合成路线

Cherney, Robert J.; Mo, Ruowei; Meyer, Dayton T.; Voss, Matthew E.; Yang, Michael G.; Santella III, Joseph B.; Duncia, John V.; Lo, Yvonne C.; Yang, Gengjie; Miller, Persymphonie B.; Scherle, Peggy A.; Zhao, Qihong; Mandlekar, Sandhya; Cvijic, Mary Ellen; Barrish, Joel C.; Decicco, Carl P.; Carter, Percy H.
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 8 p. 2425 - 2430

4746-97-81,4-环己二酮单乙二醇缩酮+

2635-13-44-溴-1,2-亚甲二氧基苯

150019-56-08-(1,3-苯并-5-二氧基)-1,4-二噁螺[4.5]癸烷-8-醇

参考文献

Bristol-Myers Squibb
Patent: US5391570 A1, 1995 ;
US 5391570 A

4746-97-81,4-环己二酮单乙二醇缩酮+

17680-04-5溴化3,4-(甲二氧基)苯基镁

150019-56-08-(1,3-苯并-5-二氧基)-1,4-二噁螺[4.5]癸烷-8-醇

参考文献

Mattson, Ronald J; Catt, John D; Sloan, Charles P; Gao; Carter, Richard B; Gentile, Anthony; Mahle, Cathy D; Matos, F Fatima; McGovern, Rachel; VanderMaelen, Cam P; Yocca, Frank D
Bioorganic and medicinal chemistry letters, 2003 , vol. 13, # 2 p. 285 - 288

4746-97-81,4-环己二酮单乙二醇缩酮+

27607-77-8三氟甲磺酸三甲基硅酯

144810-01-5

参考文献

Crawford, James J.; Kerr, William J.; McLaughlin, Mark; Morrison, Angus J.; Pauson, Peter L.; Thurston, Graeme J.
Tetrahedron, 2006 , vol. 62, # 49 p. 11360 - 11370

4746-97-81,4-环己二酮单乙二醇缩酮+

75-77-4三甲基氯硅烷

144810-01-5

参考文献

Nguyen, Henry; Oh, Seongho; Henry-Riyad, Huda; Sepulveda, Diana; Romo, Daniel
Organic Syntheses, 2012 , vol. 88, p. 121 - 137