2,6,6-三甲基环己烯-1-羧酸合成路线 （共 16 条）
反应条件
Reaktion ueber mehrere Stufen;
参考文献
Merling
Chemische Berichte, 1908 , vol. 41, p. 2064,2066
反应条件
sulfuric acid in nitromethane
T=-40°C; 1 h;
参考文献
Lyashchuk, S. N.; Skrypnik, Yu. G.; Bezrodnyi, B. P.
Russian Journal of Organic Chemistry, 1993 , vol. 29, # 1.2 p. 109 - 114
Zhurnal Organicheskoi Khimii, 1993 , vol. 29, # 1 p. 130 - 136
反应条件
potassium hydroxide; thiophenol in N,N-dimethyl-formamide
T=100°C; 8 h;
参考文献
Fehr; Galindo
Helvetica Chimica Acta, 1995 , vol. 78, # 3 p. 539 - 552
反应条件
formic acid
0.333333 h; Heating; Yields of byproduct given;
参考文献
Kadas, Istvan; Arvai, Geza; Horyath, Gabriella
Organic Preparations and Procedures International, 1998 , vol. 30, # 1 p. 79 - 85
反应条件
air
168 h; Darkness;
参考文献
Burton, Graham W.; Daroszewski, Janusz; Nickerson, James G.; Johnston, James B.; Mogg, Trevor J.; Nikiforov, Grigory B.
Canadian Journal of Chemistry, 2014 , vol. 92, # 4 p. 305 - 316
反应条件
H2O in water; acetonitrile
T=25°C; 88 h; var. pH and μ, other solvent; Product distributionRate constant;
参考文献
Allen, Annette D.; Stevenson, Andrew; Tidwell, Thomas T.
Journal of Organic Chemistry, 1989 , vol. 54, # 12 p. 2843 - 2848
反应条件
1: (i) PhLi, piperidine, (ii) /BRN= 1741705/
2: H2SO4 / acetic acid
3: (i) Li, THF, (ii) /BRN= 1900390/
View Scheme
参考文献
Koebrich,G. et al.
Justus Liebigs Annalen der Chemie, 1967 , vol. 704, p. 51 - 69
反应条件
1: H2SO4 / acetic acid
2: (i) Li, THF, (ii) /BRN= 1900390/
View Scheme
参考文献
Koebrich,G. et al.
Justus Liebigs Annalen der Chemie, 1967 , vol. 704, p. 51 - 69
反应条件
Rexyn 201 (OH form) in methanol
Yield given. Yields of byproduct given;
参考文献
Frank, Arlen W.
Journal of Heterocyclic Chemistry, 1981 , vol. 18, p. 549 - 554
反应条件
1: 93 percent / Ag2O, aq. NaOH / 8 h
2: 99percent HCO2H / 0.33 h / Heating
View Scheme
参考文献
Kadas, Istvan; Arvai, Geza; Horyath, Gabriella
Organic Preparations and Procedures International, 1998 , vol. 30, # 1 p. 79 - 85
