5,5-二甲基-2-环己烯-1-酮合成路线 （共 67 条）
反应条件
n-Butyl nitrite; ammonia
T=-78°C; 1 h;
参考文献
Matoba, Katsuhide; Morita, Takashi; Yamazaki, Takao
Chemical & Pharmaceutical Bulletin, 1983 , vol. 31, # 12 p. 4368 - 4375
反应条件
potassium; isopentyl nitrite
参考文献
Matoba, Katsuhide; Yamazaki, Takao
Chemical & Pharmaceutical Bulletin, 1982 , vol. 30, # 10 p. 3863 - 3864
反应条件
N-bromosuccinmide in tetrachloromethane
0.166667 h; Heating;
参考文献
Zegarski, Joseph; Howard, Bruce M.
Tetrahedron Letters, 1985 , vol. 26, # 11 p. 1363 - 1366
反应条件
n-Butyl nitrite; ammonia
T=-78°C; 1 h;
参考文献
Matoba, Katsuhide; Morita, Takashi; Yamazaki, Takao
Chemical & Pharmaceutical Bulletin, 1983 , vol. 31, # 12 p. 4368 - 4375
反应条件
18-crown-6 ether in benzene
7 h; Ambient temperature;
参考文献
Frimer, Aryeh A.; Gilinsky-Sharon, Pessia; Aljadeff, Gladis; Gottlieb, Hugo E.; Hameiri-Buch, Judith; et al.
Journal of Organic Chemistry, 1989 , vol. 54, # 20 p. 4853 - 4866
反应条件
1: (i) CuI, (ii) /BRN= 1209504/, (iii) /BRN= 605437/
2: Na, MeOH
View Scheme
参考文献
Salomon,R.G.; Salomon,M.F.
Journal of Organic Chemistry, 1975 , vol. 40, # 10 p. 1488 - 1492
反应条件
n-butyllithium; CuSPh; acetic acid
1.) THF, hexane, -78 deg C, 2.) -70 deg C, 12 h, 3.) -78 deg C, to RT, then reflux 4 h; Yield given. Multistep reaction;
参考文献
Kelly, T. Ross; Liu, Hshiou-ting
Journal of the American Chemical Society, 1985 , vol. 107, # 17 p. 4998 - 4999
反应条件
magnesium; copper(l) chloride in diethyl ether
1.) -20 deg C, 15 min; 2.) -40 deg C, 1 h then rt., 5.5 h;
参考文献
Kato; Hattori; Kawai; Sawa
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 11 p. 3915 - 3923
反应条件
magnesium; copper(l) chloride in diethyl ether
1.) -20 deg C; 2.) -40 deg C, then rt.;
参考文献
Kato; Hattori; Kawai; Sawa
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 11 p. 3915 - 3923
反应条件
copper(l) chloride in diethyl ether
-40 deg C, then rt.;
参考文献
Kato; Hattori; Kawai; Sawa
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 11 p. 3915 - 3923
