反式-1,3-二苯基-2-丙烯-1-醇合成路线 （共 38 条）
反应条件
1.1: pyridine; DMAP / tetrahydrofuran / 20 °C 2.1: 88 percent / aspartic acid-derived P-chirogenic diaminophosphine oxide; BSA; iPr2NEt / (η3-C3H5PdCl)2 / 3.5 h / 20 °C 3.1: SmI2 / methanol; tetrahydrofuran / 5 h / 0 - 20 °C 3.2: 87 percent / NEt3 / CH2Cl2 / 0.5 h / 20 °C 4.1: 76 percent / dimethylformamide / 50 °C 5.1: 85 percent / 2nd generation Grubbs catalyst / CH2Cl2 / 3.5 h / Heating 6.1: 72 percent / H2 / Pd/C / ethanol; ethyl acetate View Scheme
参考文献
Nemoto, Tetsuhiro; Jin, Long; Nakamura, Hiroshi; Hamada, Yasumasa
Tetrahedron Letters, 2006 , vol. 47, # 37 p. 6577 - 6581
反应条件
1: With copper(I) bromide in acetonitrile T=20°C; 0.05 h; Inert atmosphere; 2: With 1,2-bis(1,1-dimethylethyl)-3-diaziridinone in acetonitrile T=20°C; 0.333333 h;
参考文献
Zhu, Yingguang; Zhao, Baoguo; Shi, Yian
Organic Letters, 2013 , vol. 15, # 5 p. 992 - 995
反应条件
anhydrous iron chloride in toluene T=80°C; 2 h; chemoselective reaction;
参考文献
Journal of Organic Chemistry, , vol. 74, # 9 p. 3299 - 3304
反应条件
FeCl3·6H2O in nitromethane T=80°C;
参考文献
Journal of Organic Chemistry, , vol. 74, # 9 p. 3299 - 3304
反应条件
potassium tert-butylate in tetrahydrofuran T=25°C; Ramberg-Baecklund reaction; 2 h;
参考文献
Evans, Paul; Johnson, Paul; Taylor, Richard J. K.
European Journal of Organic Chemistry, 2006 , # 7 p. 1740 - 1754
反应条件
[{(η6-C6Me6)Ru(μ-Cl)Cl}2]; water; sodium formate T=100°C; 24 h; Inert atmosphere;
参考文献
Cadierno, Victorio; Crochet, Pascale; Francos, Javier; Garcia-Garrido, Sergio E.; Gimeno, Jose; Nebra, Noel
Green Chemistry, 2009 , vol. 11, # 12 p. 1992 - 2000
参考文献
Nomura
Bulletin de la Societe Chimique de France, 1925 , vol. <4> 37, p. 1246
反应条件
1: 3-hydroxy-1,3-diphenyl-prop-1-ene With (R)-(S)-Josiphos; bis(dibenzylideneacetone)-palladium(0) in benzene 0.5 h; 2: bis-diphenylphosphine in benzene T=40°C; optical yield given as percent eeenantioselective reaction;
参考文献
Butti, Pietro; Rochat, Raphael; Sadow, Aaron D.; Togni, Antonio
Angewandte Chemie - International Edition, 2008 , vol. 47, # 26 p. 4878 - 4881
反应条件
palladium dichloride in methanol T=40°C; 18 h; Inert atmosphereGreen chemistry; chemoselective reaction;
参考文献
Wang, Hu; Li, Li; Bai, Xing-Feng; Shang, Jun-Yan; Yang, Ke-Fang; Xu, Li-Wen
Advanced Synthesis and Catalysis, 2013 , vol. 355, # 2-3 p. 341 - 347
反应条件
pyridine; 4-(N,N-dimethlyamino)pyridine in tetrahydrofuran T=20°C;
参考文献
Nemoto, Tetsuhiro; Jin, Long; Nakamura, Hiroshi; Hamada, Yasumasa
Tetrahedron Letters, 2006 , vol. 47, # 37 p. 6577 - 6581
