3-(4-甲基苯甲酰)丙酸合成路线 (共 57 条)
反应条件
potassium carbonate in DMF (N,N-dimethyl-formamide) T=20°C; 3 h;
参考文献
PHARMACIA and UPJOHN COMPANY
Patent: WO2004/45616 A1, 2004 ;
Location in patent: Page/Page column 34-35 ;
反应条件
p-toluenesulfonic acid monohydrate in methanol; ethyl acetate
参考文献
Japan Tobacco Inc.
Patent: EP885869 A1, 1998 ;
反应条件
potassium carbonate in acetone esterification; Heating;
参考文献
Khan; Siddiqui
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2000 , vol. 39, # 8 p. 614 - 619
反应条件
hydrogenchloride T=25°C; 15 h;
参考文献
Kim, Choung Un; Misco, Peter F.; Luh, Bing Y.; Mansuri, Muzammil M.
Tetrahedron Letters, 1994 , vol. 35, # 19 p. 3017 - 3020
反应条件
1: Zn, aq. HCl 2: aq. H2SO4 3: (i), (ii) (heating) 4: Pd-C View Scheme
参考文献
Gensler,W.J. et al.
Journal of Organic Chemistry, 1962 , vol. 27, p. 857 - 863
反应条件
disodium hydrogenphosphate; sodium acetate; permanganate(VII) ion T=29.85°C; Oxidation; pH=6.5; Kinetics; Further Variations:TemperaturesReagents;
参考文献
Indian Journal of Chemistry - Section A Inorganic, Physical, Theoretical and Analytical Chemistry, , vol. 38, # 2 p. 183 - 186
反应条件
sodium hydroxide 1 h; Ambient temperature;
参考文献
Cignarella, Giorgio; Grella, Giuseppe; Curzu, Maria Michela
Synthesis, 1980 , # 10 p. 825 - 828
反应条件
sodium hydroxide 1 h; Ambient temperature;
参考文献
Cignarella, Giorgio; Grella, Giuseppe; Curzu, Maria Michela
Synthesis, 1980 , # 10 p. 825 - 828
反应条件
sodium hydroxide 1 h; Ambient temperaturedifferent molar ratios of reagents; Product distribution;
参考文献
Cignarella, Giorgio; Grella, Giuseppe; Curzu, Maria Michela
Synthesis, 1980 , # 10 p. 825 - 828
反应条件
(i) N2H4, KOH, HOCH2CH2OH, (ii) polyphosphoric acid; Multistep reaction;
参考文献
Gensler,W.J. et al.
Journal of Organic Chemistry, 1962 , vol. 27, p. 857 - 863