5-醛基-2-噻吩甲酸合成路线

参考文献

CHONG KUN DANG PHARMACEUTICAL CORP.
Patent: WO2004/37808 A1, 2004 ;
Location in patent: Page 14-15; 93 ;

参考文献

Moehlmann, Lennart; Ludwig, Stefan; Blechert, Siegfried
Beilstein Journal of Organic Chemistry, 2013 , vol. 9, p. 602 - 607

58268-08-92-(2-噻吩基)-1,3-二氧戊环+

124-38-9二氧化碳

4565-31-55-醛基-2-噻吩甲酸

参考文献

Mahboobi, Siavosh; Dove, Stefan; Sellmer, Andreas; Winkler, Matthias; Eichhorn, Emerich; Pongratz, Herwig; Ciossek, Thomas; Baer, Thomas; Maier, Thomas; Beckers, Thomas
Journal of Medicinal Chemistry, 2009 , vol. 52, # 8 p. 2265 - 2279

124-38-9二氧化碳+

104208-13-11,3-二甲基-2-(2-噻吩)咪唑烷

4565-31-55-醛基-2-噻吩甲酸

参考文献

Renouard, Thierry; Graetzel, Michael
Tetrahedron, 2001 , vol. 57, # 38 p. 8145 - 8150

98-03-32-噻吩甲醛

4565-31-55-醛基-2-噻吩甲酸

参考文献

Carpenter, Andrew J,; Chadwick, Derek J.
Tetrahedron, 1985 , vol. 41, # 18 p. 3803 - 3812

123-91-11,4-二氧六环+

6165-68-02-噻吩硼酸+

4565-31-55-醛基-2-噻吩甲酸

3779-27-92,2-联噻吩-5-乙醛

参考文献

Merck and Co., Inc.
Patent: US5874452 A1, 1999 ;

4565-31-55-醛基-2-噻吩甲酸

14282-64-55-羟基甲基-2-噻吩羧酸

参考文献

R-tech Ueno, Ltd.
Patent: WO2009/145360 A1, 2009 ;
Location in patent: Page/Page column 136-137 ;
WO 2009/145360 A1

4565-31-55-醛基-2-噻吩甲酸

50340-79-95-羧酸-2-噻吩甲酸甲酯

参考文献

Frizler, Maxim; Schmitz, Janina; Schulz-Fincke, Anna-Christina; Guetschow, Michael
Journal of Medicinal Chemistry, 2012 , vol. 55, # 12 p. 5982 - 5986

4565-31-55-醛基-2-噻吩甲酸+

74-88-4甲基碘

67808-64-45-醛基噻吩-2-甲酸甲酯

参考文献

Goddard
Journal of Heterocyclic Chemistry, 1991 , vol. 28, # 1 p. 17 - 28

4565-31-55-醛基-2-噻吩甲酸+

75-03-6碘乙烷

67808-65-55-甲酰基噻吩-2-羧酸乙酯

参考文献

Renouard, Thierry; Graetzel, Michael
Tetrahedron, 2001 , vol. 57, # 38 p. 8145 - 8150