2,4,6-trimethyl-pyridine; hydrogen fluoride T=120°C; 1 h;

potassium fluoride in acetonitrile

KF in acetonitrile

cesium fluoride in various solvent(s) T=130°C; 18 h;

nitronium tetrafluoroborate in dichloromethane Heating;

1: With nitric acid; trifluoroacetic anhydride 10 h; 2: With sodium disulfite 24 h;

hydrogen fluoride Behandeln der Reaktionsloesung mit Natriumnitrit;

暂无反应条件数据

1.1: 70 percent / H2 / Raney Ni / ethyl acetate 2.1: 96 percent / 2-methyl-propan-2-ol / 4 h / 40 °C 3.1: n-BuLi; tetramethylethylenediamine / diethyl ether / -78 °C 3.2: diethyl ether 4.1: methanol; CHCl3; hexane / 2 h / 0 - 20 °C 5.1: n-BuLi / tetrahydrofuran / 1 h / -78 °C 5.2: AcOH / tetrahydrofuran / -78 - 20 °C 6.1: dimethylformamide / 5 h / 20 °C 7.1: 70 percent / (COCl)2; DMF / CH2Cl2 / 2 h / Heating View Scheme

1.1: 70 percent / H2 / Raney Ni / ethyl acetate 2.1: 96 percent / 2-methyl-propan-2-ol / 4 h / 40 °C 3.1: n-BuLi; tetramethylethylenediamine / diethyl ether / -78 °C 3.2: diethyl ether 4.1: methanol; CHCl3; hexane / 2 h / 0 - 20 °C 5.1: n-BuLi / tetrahydrofuran / 1 h / -78 °C 5.2: AcOH / tetrahydrofuran / -78 - 20 °C 6.1: dimethylformamide / 5 h / 20 °C 7.1: 70 percent / (COCl)2; DMF / CH2Cl2 / 2 h / Heating 8.1: ethanol / 8 h / Heating View Scheme