2-溴-5-三氟甲苯苯胺合成路线 （共 20 条）
参考文献
E. R. Squibb and Sons, Inc.
Patent: US4062846 A1, 1977 ;
反应条件
bromine; acetic acid
参考文献
Tarrant; Lilyquist
Journal of the American Chemical Society, 1953 , vol. 75, p. 3034
反应条件
N-bromosuccinmide in 1,4-dioxane T=20°C;
参考文献
Bartoli, Sandra; Cipollone, Amalia; Squarcia, Antonella; Madami, Andrea; Fattori, Daniela
Synthesis, 2009 , # 8 art. no. P12608SS, p. 1305 - 1308
参考文献
van der Stelt,C. et al.
Arzneimittel Forschung, 1964 , vol. 14, p. 964 - 967
反应条件
1,4-diaza-bicyclo[2.2.2]octane in toluene T=60°C; 8 h;
参考文献
Yang, Jin; Li, Pinhua; Wang, Lei
Tetrahedron, 2011 , vol. 67, # 31 p. 5543 - 5549
反应条件
isopentyl nitrite in acetonitrile Heating;
参考文献
Allaire; Lyga
Synthetic Communications, 2001 , vol. 31, # 12 p. 1857 - 1861
参考文献
Rhone-Poulenc Argriculture Ltd
Patent: US5366957 A1, 1994 ;
反应条件
hydrogenchloride; sodium nitrite anschliessend Behandeln mit 50prozentig. wss. Hypophosphorigsaeure;
参考文献
van der Stelt,C. et al.
Arzneimittel Forschung, 1964 , vol. 14, p. 964 - 967
反应条件
in N,N-dimethyl-formamide 4 h; Heating / reflux;
参考文献
Amgen Inc.
Patent: US2005/250820 A1, 2005 ;
Location in patent: Page/Page column 70 ;
US 20050250820 A1
反应条件
in chloroform; N,N-dimethyl-formamide
参考文献
Tularik Inc.
Patent: US2003/139390 A1, 2003 ;
US 20030139390 A1
