4-甲基-7-硝基-3,4-二氢喹噁啉-2(1h)-酮合成路线 （共 9 条）
反应条件
1: With sodium sulfide; sodium hydrogencarbonate in methanol; water
T=30°C;
2: With acetic acid in ethanol; water
pH=1;
参考文献
Chicharro, Roberto; De Castro, Sonia; Reino, Jose L.; Aran, Vicente J.
European Journal of Organic Chemistry, 2003 , # 12 p. 2314 - 2326
反应条件
in tetrahydrofuran
T=60 - 65°C; 4 h;
参考文献
De Castro, Sonia; Chicharro, Roberto; Aran, Vicente J.
Journal of the Chemical Society. Perkin Transactions 1, 2002 , # 6 p. 790 - 802
反应条件
in nitromethane
24 h; Heating;
参考文献
De Castro, Sonia; Chicharro, Roberto; Aran, Vicente J.
Journal of the Chemical Society. Perkin Transactions 1, 2002 , # 6 p. 790 - 802
反应条件
in nitromethane
72 h; Heating;
参考文献
De Castro, Sonia; Chicharro, Roberto; Aran, Vicente J.
Journal of the Chemical Society. Perkin Transactions 1, 2002 , # 6 p. 790 - 802
反应条件
1.1: 96 percent / sodium hydrogencarbonate / ethanol; H2O
2.1: sodium hydrogen carbonate; sodium sulfide nonahydrate / methanol; H2O / 30 °C
2.2: 65 percent / Acetic acid / ethanol; H2O / pH 1
View Scheme
参考文献
Chicharro, Roberto; De Castro, Sonia; Reino, Jose L.; Aran, Vicente J.
European Journal of Organic Chemistry, 2003 , # 12 p. 2314 - 2326
反应条件
1: 97 percent / acetone / 1 h / 20 °C
2: 1.5 percent / tetrahydrofuran / 4 h / 60 - 65 °C
View Scheme
参考文献
De Castro, Sonia; Chicharro, Roberto; Aran, Vicente J.
Journal of the Chemical Society. Perkin Transactions 1, 2002 , # 6 p. 790 - 802
反应条件
1: 99 percent / ethanol / 480 h / 20 °C
2: 97 percent / acetone / 1 h / 20 °C
3: 98 percent / nitromethane / 24 h / Heating
View Scheme
参考文献
De Castro, Sonia; Chicharro, Roberto; Aran, Vicente J.
Journal of the Chemical Society. Perkin Transactions 1, 2002 , # 6 p. 790 - 802
反应条件
1: 97 percent / acetone / 1 h / 20 °C
2: 98 percent / nitromethane / 24 h / Heating
View Scheme
参考文献
De Castro, Sonia; Chicharro, Roberto; Aran, Vicente J.
Journal of the Chemical Society. Perkin Transactions 1, 2002 , # 6 p. 790 - 802
反应条件
1: 95 percent / tetrahydrofuran / 4 h / 60 - 65 °C
2: 91 percent / nitromethane / 72 h / Heating
View Scheme
参考文献
De Castro, Sonia; Chicharro, Roberto; Aran, Vicente J.
Journal of the Chemical Society. Perkin Transactions 1, 2002 , # 6 p. 790 - 802
