2-(4-甲基苯基)吡啶合成路线 （共 103 条）
反应条件
1: 91 percent / K2CO3; t-Bu3P*HBF4; Pd(OAc)2 / toluene / 110 °C 2: 95 percent / HCOONH4; Pd/C / methanol / 20 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 127, # 51 p. 18020 - 18021
反应条件
tetrakis(triphenylphosphine) palladium(0); potassium carbonate in ethanol T=100°C; Suzuki Coupling; 18 h; Inert atmosphere;
参考文献
Goggins, Sean; Rosevere, Eleanor; Bellini, Clement; Allen, Joseph C.; Marsh, Barrie J.; Mahon, Mary F.; Frost, Christopher G.
Organic and Biomolecular Chemistry, 2014 , vol. 12, # 1 p. 47 - 52
反应条件
C32H26ClN2NiP in tetrahydrofuran; 1-methyl-pyrrolidin-2-one T=85°C; 12 h; Inert atmosphere;
参考文献
Zhang, Xue-Qi; Wang, Zhong-Xia
Journal of Organic Chemistry, 2012 , vol. 77, # 7 p. 3658 - 3663
反应条件
copper(l) iodide; cesium fluoride in N,N-dimethyl-formamide T=120°C; Hiyama Coupling; 12 h; Inert atmosphere;
参考文献
Gurung, Santosh K.; Thapa, Surendra; Vangala, Adarsh S.; Giri, Ramesh
Organic Letters, 2013 , vol. 15, # 20 p. 5378 - 5381
反应条件
C60H48Cl2FeP4 in tetrahydrofuran; toluene T=100°C; 4 h; Inert atmosphere;
参考文献
Bedford, Robin B.; Hall, Mark A.; Hodges, George R.; Huwe, Michael; Wilkinson, Mark C.
Chemical Communications, 2009 , # 42 p. 6430 - 6432
反应条件
potassium tert-butylate T=110°C; 8 h;
参考文献
New Journal of Chemistry, , vol. 38, # 2 p. 827 - 836
反应条件
potassium phosphate; palladium diacetate; triphenylphosphine in 1,4-dioxane T=110°C; Suzuki-Miyaura Coupling; 7 h; Inert atmosphereSchlenk techniqueSealed tube;
参考文献
Quan, Zheng-Jun; Jing, Fu-Qiang; Zhang, Zhang; Da, Yu-Xia; Wang, Xi-Cun
European Journal of Organic Chemistry, 2013 , # 31 p. 7175 - 7183
反应条件
palladium diacetate; potassium carbonate; triphenylphosphine; copper(l) iodide in tetrahydrofuran Suzuki-Miyaura cross-coupling reaction; Heating;
参考文献
Hodgson, Paul B.; Salingue, Fabrice H.
Tetrahedron Letters, 2004 , vol. 45, # 4 p. 685 - 687
反应条件
caesium carbonate; 1,3-bis(2,4,6-trimethylphenyl)imidazolinium chloride; palladium diacetate in 1,4-dioxane T=120°C; P=37503 Torr; 24 h;
参考文献
Tetrahedron, , vol. 63, # 3 p. 682 - 689
反应条件
in N,N-dimethyl-formamide T=100°C; 1 h; Inert atmosphere;
参考文献
Deng, James Z.; Paone, Daniel V.; Ginnetti, Anthony T.; Kurihara, Hideki; Dreher, Spencer D.; Weissman, Steven A.; Stauffer, Shaun R.; Burgey, Christopher S.
Organic Letters, 2009 , vol. 11, # 2 p. 345 - 347
