4-(三甲基甲硅烷基)-1-硝基苯合成路线 （共 18 条）
反应条件
XeF2 in hexafluorobenzene T=20°C; 1 h; Pyrex.(R). vessel;
参考文献
Lothian, Aileen P.; Ramsden, Christopher A.; Shaw, Maxine M.; Smith, Rachel G.
Tetrahedron, 2011 , vol. 67, # 15 p. 2788 - 2793
反应条件
in sulfuric acid; acetic acid T=50°C;
参考文献
Seconi, Giancarlo; Eaborn, Colin
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1981 , p. 931 - 934
反应条件
1: 2) 5percent H2SO4 / 1) Et4NF*2H2O / 1) HMPA 3: 48 percent Chromat. / KOtBu / dimethylformamide / 3 h / 80 °C View Scheme
参考文献
Effenberger, Franz; Spiegler, Wolfgang
Chemische Berichte, 1985 , vol. 118, # 9 p. 3872 - 3899
反应条件
hydrogen; palladium 10 on activated carbon in ethanol P=760.051 Torr;
参考文献
ASTRAZENECA AB; ASTRAZENECA UK LIMITED
Patent: WO2005/80328 A1, 2005 ;
Location in patent: Page/Page column 12; 34 ;
WO 2005/080328 A1
反应条件
water; tris-(dibenzylideneacetone)dipalladium(0) in N,N-dimethyl-formamide
T=100°C; 24 h;
参考文献
McNeill, Eric; Barder, Timothy E.; Buchwald, Stephen L.
Organic Letters, 2007 , vol. 9, # 19 p. 3785 - 3788
反应条件
nitric acid; acetic anhydride
1.5 h; Reflux;
参考文献
Lothian, Aileen P.; Ramsden, Christopher A.; Shaw, Maxine M.; Smith, Rachel G.
Tetrahedron, 2011 , vol. 67, # 15 p. 2788 - 2793
反应条件
1: para-nitro iodo-benzene With phenyllithium in tetrahydrofuran; diethyl ether; cyclohexane
T=-28°C; 2.77778E-06 h; Microflow reactor;
2: chloro-trimethyl-silane in tetrahydrofuran; diethyl ether; cyclohexane
T=-28°C; 0.00255556 h; Microflow reactor;
参考文献
Nagaki, Aiichiro; Kim, Heejin; Yoshida, Jun-ichi
Angewandte Chemie - International Edition, 2009 , vol. 48, # 43 p. 8063 - 8065
反应条件
1: para-nitro iodo-benzene With phenyllithium in tetrahydrofuran; diethyl ether; cyclohexane
T=-28°C; 2.77778E-06 h; Microflow reactor;
2: trimethylsilyl trifluoromethanesulfonate in tetrahydrofuran; diethyl ether; cyclohexane
T=-28°C; 0.00255556 h; Microflow reactor;
参考文献
Nagaki, Aiichiro; Kim, Heejin; Yoshida, Jun-ichi
Angewandte Chemie - International Edition, 2009 , vol. 48, # 43 p. 8063 - 8065
反应条件
HNO3 in acetic anhydride
(CH3)3SiC6H5 and 90percent HNO3 in acetic anhydride; various temp.; various product ratio;;
参考文献
Speier
Journal of the American Chemical Society, 1953 , vol. 75, p. 2930
Full Text View citing articles Show Details
Gmelin Handbook: Si: MVol.C, 21, page 66 - 68
反应条件
bis(η3-allyl-μ-chloropalladium(II)); triethyl phosphite
T=110°C; 1.8 h;
参考文献
Yamamoto, Keiji; Suzuki, Shigeaki; Tsuji, Jiro
Tetrahedron Letters, 1980 , vol. 21, p. 1653 - 1656
