三环[16.2.2.28,11]二十四碳-8,10,18,20(1),21,23-六烯合成路线 (共 18 条)
反应条件
hydrogen; platinum(IV) oxide in ethyl acetate
T=21°C; P=760 Torr;
参考文献
Romero, Miguel A.; Fallis, Alex G.
Tetrahedron Letters, 1994 , vol. 35, # 27 p. 4711 - 4714
反应条件
Raney nickel W-2 in 1,4-dioxane
1 h; Heating;
参考文献
Miyahara, Yuji; Inazu, Takahiko; Yoshino, Tamotsu
Journal of Organic Chemistry, 1984 , vol. 49, # 7 p. 1177 - 1182
反应条件
hydrogen; palladium on activated charcoal
参考文献
Glatzhofer, Daniel T.; Longone, Daniel T.
Tetrahedron Letters, 1983 , vol. 24, # 41 p. 4413 - 4416
反应条件
sodium hydroxide; tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran
Suzuki-Miyaura coupling; Heating;
参考文献
Smith, Beverly B.; Hill, Darron E.; Cropp, T. Ashton; Walsh, Rosa D.; Cartrette, David; Hipps, Sherry; Shachter, Amy M.; Pennington, William T.; Kwochka, William R.
Journal of Organic Chemistry, 2002 , vol. 67, # 15 p. 5333 - 5337
反应条件
1: 42 percent / t-BuOK / tetrahydrofuran / 0.5 h / -78 °C
2: 9 percent / Pd(PPh3)4, CuI, nBuNH2 / tetrahydrofuran / 25 h / 21 °C
3: 50 percent / H2 / PtO2 / ethyl acetate / 21 °C / 760 Torr
View Scheme
参考文献
Romero, Miguel A.; Fallis, Alex G.
Tetrahedron Letters, 1994 , vol. 35, # 27 p. 4711 - 4714
反应条件
1: 9 percent / Pd(PPh3)4, CuI, nBuNH2 / tetrahydrofuran / 25 h / 21 °C
2: 50 percent / H2 / PtO2 / ethyl acetate / 21 °C / 760 Torr
View Scheme
参考文献
Romero, Miguel A.; Fallis, Alex G.
Tetrahedron Letters, 1994 , vol. 35, # 27 p. 4711 - 4714
反应条件
1: 9 percent / Pd(PPh3)4, CuI, nBuNH2 / tetrahydrofuran / 25 h / 21 °C
2: 50 percent / H2 / PtO2 / ethyl acetate / 21 °C / 760 Torr
View Scheme
参考文献
Romero, Miguel A.; Fallis, Alex G.
Tetrahedron Letters, 1994 , vol. 35, # 27 p. 4711 - 4714
反应条件
1: 98 percent / K2CO3 / methanol / 6 h / 21 °C
2: 9 percent / Pd(PPh3)4, CuI, nBuNH2 / tetrahydrofuran / 25 h / 21 °C
3: 50 percent / H2 / PtO2 / ethyl acetate / 21 °C / 760 Torr
View Scheme
参考文献
Romero, Miguel A.; Fallis, Alex G.
Tetrahedron Letters, 1994 , vol. 35, # 27 p. 4711 - 4714
反应条件
hydrogenchloride; amalgamated zinc; acetic acid
参考文献
Abell; Cram
Journal of the American Chemical Society, 1954 , vol. 76, p. 4406,4410
反应条件
1: AlCl3; CS2
2: N2H4+H2O; KOH; diethylene glycol
3: H2SO4
4: sodium; xylene
5: acetic acid; amalgamated zinc; aqueous HCl
View Scheme
参考文献
Abell; Cram
Journal of the American Chemical Society, 1954 , vol. 76, p. 4406,4410