2-氯甲基吡啶合成路线

参考文献

VERNALIS (RandD) LIMITED
Patent: WO2009/156737 A1, 2009 ;
Location in patent: Page/Page column 32 ;
WO 2009/156737 A1

参考文献

Zhang, Jun; Cui, Huiling; Hojo, Masashi; Shuang, Shaomin; Dong, Chuan
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 1 p. 343 - 346

931-19-12-甲基吡啶氧化物→4377-33-72-氯甲基吡啶

参考文献

Kumar, Prabhat; Misra
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1997 , vol. 36, # 11 p. 1000 - 1004

931-19-12-甲基吡啶氧化物+75-44-5光气→4377-33-72-氯甲基吡啶

参考文献

The Dow Chemical Company
Patent: US4221913 A1, 1980 ;

109-06-82-甲基吡啶+87-90-1三氯异氰尿酸+55-21-0苯甲酰胺→4377-33-72-氯甲基吡啶

参考文献

Rutgerswerke Aktiengesellschaft
Patent: US4719298 A1, 1988 ;

694-59-7吡啶-N-氧化物→4377-33-72-氯甲基吡啶

参考文献

Bayer Corporation; Bayer Aktiengesellschaft
Patent: US6218431 B1, 2001 ;
US 6218431 B1

→4377-33-72-氯甲基吡啶

参考文献

Merck and Co., Inc.
Patent: US2002/147203 A1, 2002 ;

1007-49-42-吡啶乙酸甲酯→4377-33-72-氯甲基吡啶

参考文献

Weidmann, Klaus; Herling, Andreas W.; Lang, Hans-Jochen; Scheunemann, Karl-Heinz; Rippel, Robert; et al.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 3 p. 438 - 450

586-98-12-吡啶甲醇+644-97-3苯基二氯化磷→4377-33-72-氯甲基吡啶

参考文献

Kermagoret, Anthony; Tomicki, Falk; Braunstein, Pierre
Dalton Transactions, 2008 , # 22 p. 2945 - 2955

109-06-82-甲基吡啶→4377-33-72-氯甲基吡啶+4377-35-92-(二氯甲基)吡啶

参考文献

Newkome, George R.; Kiefer, Garry E.; Yuan-Jiao Xia; Gupta, Vinod K.
Synthesis, 1984 , # 8 p. 676 - 679