5-甲基环己烷-1,3-二酮合成路线 （共 53 条）
反应条件
bromine; acetic acid
参考文献
Cleaver,L. et al.
Australian Journal of Chemistry, 1976 , vol. 29, p. 1989 - 2001
反应条件
toluene-4-sulfonic acid in benzene 8 h; Heating;
参考文献
Foote, Kevin M; Hayes, Christopher J; John, Matthew P; Pattenden, Gerald
Organic and biomolecular chemistry, 2003 , vol. 1, # 22 p. 3917 - 3948
反应条件
toluene-4-sulfonic acid in ethanol 24 h; Ambient temperature;
参考文献
Schinzer, Dieter; Fessner, Klaus; Ruppelt, Martin
Liebigs Annalen der Chemie, 1992 , # 2 p. 139 - 144
反应条件
1: 5-methyl-cyclohexane-1,3-dione With bromine; sodium acetate; acetic acid
T=15 - 20°C;
2: thiourea T=100°C; 1 h;
参考文献
BOEHRINGER INGELHEIM INTERNATIONAL GMBH; VAN DER VEEN, Lars; MC CONNELL, Darryl; SCHNEIDER, Siegfried; GRAUERT, Matthias; SCHOOP, Andreas; WUNBERG, Tobias
Patent: WO2010/122091 A1, 2010 ;
Location in patent: Page/Page column 15 ;
WO 2010/122091 A1
反应条件
1: bromine; acetic acid / 0.58 h
2: sodium acetate / acetic acid / 3 h / 100 °C
View Scheme
参考文献
Babaoglu, Kerim; Brizgys, Gediminas; Cha, Jake; Chen, Xiaowu; Guo, Hongyan; Halcomb, Randall L.; Han, Xiaochun; Huang, Richard; Liu, Hongtao; McFadden, Ryan; Mitchell, Michael L.; Qi, Yingmei; Roethle, Paul A.; Xu, Lianhong; Yang, Hong
Patent: US2013/281433 A1, 2013 ;
反应条件
in dichloromethane
T=20°C; 24 h; Inert atmosphere;
参考文献
Grieco, Liane M.; Halliday, Gary A.; Junk, Christopher P.; Lustig, Steven R.; Marshall, William J.; Petrov, Viacheslav A.
Journal of Fluorine Chemistry, 2011 , vol. 132, # 12 p. 1198 - 1206
反应条件
indium trifluoromethanesulfonate; oxygen; palladium diacetate in 1,2-dichloro-ethane
T=75°C; P=760.051 Torr; 18 h; Schlenk technique;
参考文献
Zheng, Meifang; Huang, Liangbin; Wu, Wanqing; Jiang, Huanfeng
Organic Letters, 2013 , vol. 15, # 8 p. 1838 - 1841
反应条件
1: sulfonyl azide / |Inert atmosphere
2: tris(triphenylphosphine)ruthenium(II) chloride / toluene / 8 h / 70 °C / |Inert atmosphere
View Scheme
参考文献
Xia, Likai; Lee, Yong Rok
European Journal of Organic Chemistry, 2014 , vol. 2014, # 16 p. 3430 - 3442
参考文献
Toray Industries, Inc.
Patent: US6215016 B1, 2001 ;
参考文献
Tada, Masahiro; Takakuwa, Takako; Nagai, Masashi; Yoshii, Takao
Agricultural and Biological Chemistry, 1990 , vol. 54, # 11 p. 3061 - 3063
