2,2,2-三氟苯乙酮合成路线 （共 295 条）
反应条件
n-butyllithium
1) Et2O, 0 deg C, 45 min, 2) Et2O, 0 deg C, 2 to 3 h; Yield given. Multistep reaction;
参考文献
Muzard; Portella
Synthesis, 1992 , # 10 p. 965 - 968
反应条件
1: 72 percent / NaBH4, aq. NaOH / methanol / 0.25 h / 18 - 25 °C
2: 41 percent / AlCl3 / 5 h / 50 - 60 °C
View Scheme
参考文献
Burgess, David A.; Finn, Michael F.; Jordan, David; Rae, Ian D.; Walters, Barry D.
Australian Journal of Chemistry, 1984 , vol. 37, # 8 p. 1769 - 1773
反应条件
1: 4,4,4-trifluoro-1-(N-methoxy-N-methylamino)-1-benzyl-1-(trimethylsiloxyl)-2-butyne With tetrabutyl ammonium fluoride in tetrahydrofuran; diethyl ether
T=-15°C; 0.166667 h;
2: 2,2,2-Trifluoro-1-phenyl-ethanone in tetrahydrofuran; diethyl ether
T=20°C; 1 h;
参考文献
Jeong, In Howa; Jeon, Sung Lan; Kim, Bum Tae
Tetrahedron Letters, 2003 , vol. 44, # 38 p. 7213 - 7216
反应条件
in gas
Irradiation (UV/VIS); flash photolysis of CF3COC6H5;; determination by IR;;
参考文献
Carlson, C. A.; Pimentel, G. C.
Journal of Chemical Physics, 1966 , vol. 44, p. 4053 - 4054
反应条件
in diethyl ether
0.5 h;
参考文献
Dolenc, Darko; Plesnicar, Bozo
Journal of Organic Chemistry, 2006 , vol. 71, # 21 p. 8028 - 8036
参考文献
Kazennikova,G.V. et al.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1961 , p. 985 - 988
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1961 , # 6 p. 1066 - 1069
反应条件
1: With N,N,N',N,-tetramethylethylenediamine in toluene
T=20°C; 10 h; Inert atmosphere;
2: With water; ammonium chloride in toluene
参考文献
Genov, Miroslav; Martinez-Ilarduya, Jesus M.; Calvillo-Barahona, Mercedes; Espinet, Pablo
Organometallics, 2010 , vol. 29, # 23 p. 6402 - 6407
参考文献
Hub,L.; Mosher,H.S.
Journal of Organic Chemistry, 1970 , vol. 35, # 11 p. 3691 - 3694
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Murata; Goto; Fujiyama; Mishima; Fujio; Tsuno
Bulletin of the Chemical Society of Japan, 1990 , vol. 63, # 4 p. 1129 - 1137
Title/Abstract Full Text View citing articles Show Details
Liu, Kwang-Ting; Wu, Yuh Wern
Tetrahedron Letters, 1986 , vol. 27, # 31 p. 3623 - 3626
反应条件
1: Br2, FeCl3
2: LiAlH4
View Scheme
参考文献
Stewart,R.; van der Linden,R.
Canadian Journal of Chemistry, 1960 , vol. 38, p. 399 - 406
反应条件
1: 1.) n-BuLi / 1.) Et2O, hexane, 0 deg C, 45 min, 2.) r.t., 2 h
2: hydrolysis
3: KMnO4
View Scheme
参考文献
De Nanteuil
Tetrahedron Letters, 1991 , vol. 32, # 22 p. 2467 - 2468
