反应条件
1: 1.) magnesium / 1.) ether, 2.) ether, room temperature, 1 h 2: 96 percent / toluene-p-sulphonic acid, sulphuric acid / tetrahydrofuran / 0.08 h 3: 94 percent / 22 h / 110 °C 4: 80 percent / conc. hydrochloric acid, hydrogen / 10percent Pd/C / methanol / atmospheric pressure 5: 1.) lithium di-isopropylamide, 2.) MoOPH / 1.) THF, -78 deg C, 2.) -78 deg C -> room temperature, 2-3 h View Scheme
参考文献
Hollinshead, David M.; Howell, S. Christopher; Ley, Steven V.; Mahon, Michael; Ratcliffe, Norman M.; Worthington, Paul A.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 7 p. 1579 - 1589
