2-溴-4-甲氧基苯甲醛合成路线 （共 12 条）
反应条件
1: With n-butyllithium; N,N,N',N,-tetramethylethylenediamine Inert atmosphere; 2: With carbon tetrabromide Inert atmosphere; regioselective reaction;
参考文献
Melnes, Silje; Bayer, Annette; Gautun, Odd Reidar
Tetrahedron, 2012 , vol. 68, # 40 p. 8463 - 8471
反应条件
carbon tetrabromide Inert atmosphere;
参考文献
Baechler, Simone A.; Fehr, Markus; Habermeyer, Michael; Hofmann, Andreas; Merz, Karl-Heinz; Fiebig, Heinz-Herbert; Marko, Doris; Eisenbrand, Gerhard
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 3 p. 814 - 823
反应条件
potassium carbonate in methanol; N,N-dimethyl-formamide T=100°C; 2 h;
参考文献
AJINOMOTO CO., INC.
Patent: US2011/82109 A1, 2011 ;
Location in patent: Page/Page column 35 ;
US 20110082109 A1
反应条件
AlCl3, aluminium chloride in dichloromethane T=20°C; Friedel Crafts acylation; Inert atmosphereCooling with ice;
参考文献
Hu, Bao; Xing, Siyang; Ren, Jun; Wang, Zhongwen
Tetrahedron, 2010 , vol. 66, # 30 p. 5671 - 5674
反应条件
1: With titanium tetrachloride in dichloromethane T=0 - 20°C; 1.25 h; 2: With hydrogenchloride in dichloromethane Further stages. Title compound not separated from byproducts.;
参考文献
Moorthy, Jarugu Narasimha; Samanta, Subhas
Journal of Organic Chemistry, 2007 , vol. 72, # 25 p. 9786 - 9789
反应条件
1: With n-butyllithium; N,N,N'-trimethyl-ethylenediamine in tetrahydrofuran 2: With 1,2-dibromo-1,1,2,2-tetrachloroethane in tetrahydrofuran Further stages. Title compound not separated from byproducts.;
参考文献
Bower, John F.; Szeto, Peter; Gallagher, Timothy
Organic and Biomolecular Chemistry, 2007 , vol. 5, # 1 p. 143 - 150
反应条件
bromine T=150°C; Belichtung; Erhitzen des Reaktionsprodukts mit CaCO3 und H2O;
参考文献
Alberola et al.
Anales de la Real Sociedad Espanola de Fisica y Quimica, Serie B: Quimica, 1959 , vol. 55, p. 683,689
反应条件
alkaline permanganate
参考文献
Hodgson; Jenkinson
Journal of the Chemical Society, 1927 , p. 1741
反应条件
sodium tetrahydroborate in tetrahydrofuran; methanol T=20°C; 1.5 h;
参考文献
Bower, John F.; Szeto, Peter; Gallagher, Timothy
Organic and Biomolecular Chemistry, 2007 , vol. 5, # 1 p. 143 - 150
反应条件
1: phenyl-(2-trimethylsilanylmethyl-cyclopropyl)-methanone With titanium tetrachloride in dichloromethane
0.5 h;
2: 2-bromo-4-methoxy-benzaldehyde in dichloromethane
T=-78°C; 1 h;
参考文献
Yadav, Veejendra K.; Balamurugan, Rengarajan
Organic Letters, 2003 , vol. 5, # 23 p. 4281 - 4284
