alpha-溴环己烷乙酸乙酯合成路线 （共 6 条）
反应条件
thionyl chloride; bromine anschliessend Behandeln mit Aethanol;
参考文献
Richter, Hans G.F.; Benson; Bleicher; Blum; Chaput; Clemann; Feng; Gardes; Grether; Hartman; Kuhn; Martin; Plancher; Rudolph; Schuler; Taylor
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 4 p. 1134 - 1140
反应条件
potassium tert-butylate in tetrahydrofuran; tert-butyl alcohol
参考文献
Brown,H.C. et al.
Journal of the American Chemical Society, 1968 , vol. 90, p. 1911 - 1913
反应条件
1: diazoacetic acid ethyl ester With N-bromosuccinmide; 1,8-diazabicyclo[5.4.0]undec-7-ene in dichloromethane T=0°C; 0.0833333 h; 2: cyclohexane With Rh2(triphenylacetate)4 T=0 - 20°C; regioselective reaction;
参考文献
Bonge, Hanne Therese; Hansen, Tore
Synthesis, 2009 , # 1 p. 91 - 96
反应条件
1: bromine / Reflux 2: 0 - 20 °C View Scheme
参考文献
Richter, Hans G.F.; Benson; Bleicher; Blum; Chaput; Clemann; Feng; Gardes; Grether; Hartman; Kuhn; Martin; Plancher; Rudolph; Schuler; Taylor
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 4 p. 1134 - 1140
参考文献
Richter, Hans G.F.; Benson; Bleicher; Blum; Chaput; Clemann; Feng; Gardes; Grether; Hartman; Kuhn; Martin; Plancher; Rudolph; Schuler; Taylor
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 4 p. 1134 - 1140
参考文献
Reetz,M. et al.
Justus Liebigs Annalen der Chemie, 1973 , p. 599 - 610
