N-(4-氨基苯甲酰)-L-谷氨酸合成路线 （共 26 条）
反应条件
palladium on carbon; hydrazine hydrate in ethanol T=80°C; 2.5 h;
参考文献
Yilmaz, Hayrullah; Topal, Giray; Cakmak, Resit; Hosgoren, Halil
Chirality, 2010 , vol. 22, # 2 p. 252 - 257
反应条件
sodium hydroxide; water in methanol T=23°C; 4 h;
参考文献
Maunder, Peter; Finglas, Paul M.; Mallet, Anthony I.; Mellon, Fred A.; Aaqib Razzaque; Ridge, Brian; Vahteristo, Liisa; Witthoeft, Cornelia
Journal of the Chemical Society - Perkin Transactions 1, 1999 , # 10 p. 1311 - 1323
反应条件
1: 79 percent / SOCl2 / 18 h / Ambient temperature 2: 70 percent / HOBt, DCC, DIEA / tetrahydrofuran / 48 h / -5 °C 3: 61 percent / NaOH, H2O / methanol / 4 h / 23 °C View Scheme
参考文献
King; Acheson; Spensley
Journal of the Chemical Society, 1949 , p. 1401,1404
参考文献
King; Spensley; Nimmo-Smith
Nature (London, United Kingdom), 1948 , vol. 162, p. 153
反应条件
1: 70 percent / HOBt, DCC, DIEA / tetrahydrofuran / 48 h / -5 °C 2: 61 percent / NaOH, H2O / methanol / 4 h / 23 °C View Scheme
参考文献
Maunder, Peter; Finglas, Paul M.; Mallet, Anthony I.; Mellon, Fred A.; Aaqib Razzaque; Ridge, Brian; Vahteristo, Liisa; Witthoeft, Cornelia
Journal of the Chemical Society - Perkin Transactions 1, 1999 , # 10 p. 1311 - 1323
反应条件
1: 1.) n-BuLi / 1.) ether, hexane, -78 deg C, 2 h, 2.) ether, hexane, -78 deg C to r.t. 2: 70 percent / HOBt, DCC, DIEA / tetrahydrofuran / 48 h / -5 °C 3: 61 percent / NaOH, H2O / methanol / 4 h / 23 °C View Scheme
参考文献
Maunder, Peter; Finglas, Paul M.; Mallet, Anthony I.; Mellon, Fred A.; Aaqib Razzaque; Ridge, Brian; Vahteristo, Liisa; Witthoeft, Cornelia
Journal of the Chemical Society - Perkin Transactions 1, 1999 , # 10 p. 1311 - 1323
反应条件
1: 70 percent / HOBt, DCC, DIEA / tetrahydrofuran / 48 h / -5 °C 2: 61 percent / NaOH, H2O / methanol / 4 h / 23 °C View Scheme
参考文献
Maunder, Peter; Finglas, Paul M.; Mallet, Anthony I.; Mellon, Fred A.; Aaqib Razzaque; Ridge, Brian; Vahteristo, Liisa; Witthoeft, Cornelia
Journal of the Chemical Society - Perkin Transactions 1, 1999 , # 10 p. 1311 - 1323
反应条件
1: 78 percent / CH2Cl2 / 1 h / Ambient temperature 2: 1.) n-BuLi / 1.) ether, hexane, -78 deg C, 2 h, 2.) ether, hexane, -78 deg C to r.t. 3: 70 percent / HOBt, DCC, DIEA / tetrahydrofuran / 48 h / -5 °C 4: 61 percent / NaOH, H2O / methanol / 4 h / 23 °C View Scheme
参考文献
Maunder, Peter; Finglas, Paul M.; Mallet, Anthony I.; Mellon, Fred A.; Aaqib Razzaque; Ridge, Brian; Vahteristo, Liisa; Witthoeft, Cornelia
Journal of the Chemical Society - Perkin Transactions 1, 1999 , # 10 p. 1311 - 1323
反应条件
1: benzene 2: aqueous hydrochloric acid 3: palladium; ethanol / Hydrogenation View Scheme
参考文献
Yoshida; Imaki; Akagi
Yakugaku Zasshi, 1949 , vol. 69, p. 457
Chem.Abstr., 1950 , p. 3442
反应条件
phosphate-buffered saline pH=7.4; UV-irradiation;
参考文献
Vorobey, Pavel; Steindal, Arnfinn Engeset; Off, Morten Kristian; Vorobey, Alexander; Moan, Johan
Photochemistry and Photobiology, 2006 , vol. 82, # 3 p. 817 - 822
