6-氯尿嘧啶合成路线

参考文献

Raoof, Ali; Depledge, Paul; Hamilton, Niall M.; Hamilton, Nicola S.; Hitchin, James R.; Hopkins, Gemma V.; Jordan, Allan M.; Maguire, Laura A.; McGonagle, Alison E.; Mould, Daniel P.; Rushbrooke, Mathew; Small, Helen F.; Smith, Kate M.; Thomson, Graeme J.; Turlais, Fabrice; Waddell, Ian D.; Waszkowycz, Bohdan; Watson, Amanda J.; Ogilvie, Donald J.
Journal of Medicinal Chemistry, 2013 , vol. 56, # 16 p. 6352 - 6370

6320-15-66-氯-2,4-甲氧基嘧啶

4270-27-36-氯尿嘧啶

参考文献

Iwata, Masaki; Bruice, Thomas C.; Carrell, H. L.; Glusker, Jenny P,
Journal of the American Chemical Society, 1980 , vol. 102, # 15 p. 5036 - 5044

67-52-7巴比妥酸

4270-27-36-氯尿嘧啶

参考文献

Todorovic, Nick; Giacomelli, Andrew; Hassell, John A.; Frampton, Christopher S.; Capretta, Alfredo
Tetrahedron Letters, 2010 , vol. 51, # 46 p. 6037 - 6040

4270-27-36-氯尿嘧啶+

95-55-6邻氨基苯酚

105147-86-2

参考文献

Shinkai, Seiji; Kawase, Akito; Yamaguchi, Toshiro; Manabe, Osamu; Wada, Yoshikazu; et al.
Journal of the American Chemical Society, 1989 , vol. 111, # 13 p. 4928 - 4935

4270-27-36-氯尿嘧啶+

74-89-5甲胺

34284-87-26-甲氨基尿嘧啶

参考文献

Raoof, Ali; Depledge, Paul; Hamilton, Niall M.; Hamilton, Nicola S.; Hitchin, James R.; Hopkins, Gemma V.; Jordan, Allan M.; Maguire, Laura A.; McGonagle, Alison E.; Mould, Daniel P.; Rushbrooke, Mathew; Small, Helen F.; Smith, Kate M.; Thomson, Graeme J.; Turlais, Fabrice; Waddell, Ian D.; Waszkowycz, Bohdan; Watson, Amanda J.; Ogilvie, Donald J.
Journal of Medicinal Chemistry, 2013 , vol. 56, # 16 p. 6352 - 6370

4270-27-36-氯尿嘧啶

4269-94-76-碘尿嘧啶

参考文献

JANSSEN PHARMACEUTICA N.V.
Patent: WO2007/79214 A2, 2007 ;
Location in patent: Page/Page column 115-116 ;
WO 2007/079214 A2

4270-27-36-氯尿嘧啶+

156-43-4对乙氧基苯胺

21333-07-3

参考文献

Klein, Robert S.; Lenzi, Michelle; Lim, Timothy H.; Hotchkiss, Kylie A.; Wilson, Phyllis; Schwartz, Edward L.
Biochemical Pharmacology, 2001 , vol. 62, # 9 p. 1257 - 1263

4270-27-36-氯尿嘧啶+

108-44-13-甲基苯胺

21332-93-4

参考文献

Dickens, Michael P.; Roxburgh, Patricia; Hock, Andreas; Mezna, Mokdad; Kellam, Barrie; Vousden, Karen H.; Fischer, Peter M.
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 22 p. 6868 - 6877

4270-27-36-氯尿嘧啶+

95-53-4邻甲苯胺

21332-92-3

参考文献

Dickens, Michael P.; Roxburgh, Patricia; Hock, Andreas; Mezna, Mokdad; Kellam, Barrie; Vousden, Karen H.; Fischer, Peter M.
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 22 p. 6868 - 6877

4270-27-36-氯尿嘧啶

21428-20-6

参考文献

Murray, Paul E; McNally, Virginia A; Lockyer, Stacey D; Williams, Kaye J; Stratford, Ian J; Jaffar, Mohammed; Freeman, Sally
Bioorganic and medicinal chemistry, 2002 , vol. 10, # 3 p. 525 - 530