4-氟-alpha,alpha-二苯基苯甲醇合成路线 (共 17 条)
反应条件
palladium diacetate; caesium carbonate; triphenylphosphine in o-xylene T=150°C; 16 h; Inert atmosphere;
参考文献
Bour, James R.; Green, Jacob C.; Winton, Valerie J.; Johnson, Jeffrey B.
Journal of Organic Chemistry, 2013 , vol. 78, # 4 p. 1665 - 1669
反应条件
copper diacetate; [RhCl(η2:η2-cycloocta-1,5-diene)]2 in o-xylene Heating;
参考文献
Uto, Toshihiko; Shimizu, Masaki; Ueura, Kenji; Tsurugi, Hayato; Satoh, Tetsuya; Miura, Masahiro
Journal of Organic Chemistry, 2008 , vol. 73, # 1 p. 298 - 300
反应条件
formic acid 0.0833333 h; Heating;
参考文献
Andrews, Adrian F.; Mackie, Raymond K.; Walton, John C.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1980 , p. 96 - 102
反应条件
1: With [RhCl(η2:η2-cycloocta-1,5-diene)]2; potassium carbonate in toluene
T=90 - 110°C;
2: With hydrogenchloride in water; toluene
参考文献
Liao, Yuan-Xi; Xing, Chun-Hui; Hu, Qiao-Sheng
Organic Letters, 2012 , vol. 14, # 6 p. 1544 - 1547
反应条件
1: 1-bromo-4-fluorobenzene With iodine; magnesium in diethyl ether
1.5 h; Reflux;
2: benzophenone in diethyl ether
Reflux;
参考文献
Weber, Cameron C.; Masters, Anthony F.; Maschmeyer, Thomas
Organic and Biomolecular Chemistry, 2013 , vol. 11, # 15 p. 2534 - 2542
反应条件
1: in various solvent(s)
3 h; Heating;
2: With hydrogenchloride
Further stages.;
参考文献
McNaughton-Smith, Grant A.; Burns, J. Ford; Stocker, Jonathan W.; Rigdon, Gregory C.; Creech, Christopher; Arlington, Susan; Shelton, Tara; De Franceschi, Lucia
Journal of Medicinal Chemistry, 2008 , vol. 51, # 4 p. 976 - 982
反应条件
1: ethanol / Einleiten von Chlorwasserstoff
2: diethyl ether
View Scheme
参考文献
Bowden; Watkins
Journal of the Chemical Society, 1940 , p. 1249,1254
反应条件
in tetrahydrofuran
0.833333 h; Heating;
参考文献
Arnett, Edward M.; Flowers II, Robert A.; Ludwig, Richard T.; Meekhof, Alison E.; Walek, Stuart A.
Journal of Physical Organic Chemistry, 1997 , vol. 10, # 7 p. 499 - 513
参考文献
Bowden; Watkins
Journal of the Chemical Society, 1940 , p. 1249,1254
参考文献
Bowden; Watkins
Journal of the Chemical Society, 1940 , p. 1249,1254