beta-丙氨酸乙酯盐酸盐合成路线 （共 27 条）
反应条件
thionyl chloride T=-10°C; 2 h; Reflux;
参考文献
Liao, Vivian; Liu, Tao; Codd, Rachel
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 19 p. 6200 - 6204
反应条件
1: ethanol With thionyl chloride T=-10°C; 0.5 h; 2: 3-aminopropionic acid hydrochloride in ethanol T=-10 - 40°C;
参考文献
Nejman, Michal; Sliwinska, Anna; Zwierzak, Andrzej
Tetrahedron, 2005 , vol. 61, # 35 p. 8536 - 8541
反应条件
triphenylphosphine in tetrahydrofuran; water 12 h; Ambient temperature;
参考文献
Knouzi, Noureddine; Vaultier, Michel; Carrie, Robert
Bulletin de la Societe Chimique de France, 1985 , # 5 p. 815 - 819
参考文献
Weitman, Michal; Lerman, Keti; Nudelman, Abraham; Major, Dan Thomas; Hizi, Amnon; Herschhorn, Alon
European Journal of Medicinal Chemistry, 2011 , vol. 46, # 2 p. 447 - 467
反应条件
1: 84 percent / NaN3 / dimethylsulfoxide / Ambient temperature 2: 90 percent / triphenylphosphine / tetrahydrofuran; H2O / 12 h / Ambient temperature View Scheme
参考文献
Knouzi, Noureddine; Vaultier, Michel; Carrie, Robert
Bulletin de la Societe Chimique de France, 1985 , # 5 p. 815 - 819
反应条件
hydrogenchloride; bis-[(trifluoroacetoxy)iodo]benzene 1) acetonitrile, water, 60-62 deg C, 2) water; Yield given. Multistep reaction;
参考文献
Loudon, G. Marc; Radhakrishna, A. S.; Almond, Merrick R.; Blodgett, James K.; Boutin, Raymond H.
Journal of Organic Chemistry, 1984 , vol. 49, # 22 p. 4272 - 4276
反应条件
1: ethyl 3-aminopropanoate hydrochloride With carbon dioxide; 1,1,1,3,3,3-hexamethyl-disilazane 5 h; Heating; 2: phosgene in toluene T=25°C; Further stages.;
参考文献
Lebedev; Lebedeva; Sheludyakov; Ovcharuk; Kovaleva; Ustinova
Russian Journal of General Chemistry, 2006 , vol. 76, # 7 p. 1069 - 1080
反应条件
1: 40 percent / triethylamine / benzene / 2 h / Heating 2: toluene / 0 °C View Scheme
参考文献
Lebedev; Lebedeva; Sheludyakov; Ovcharuk; Kovaleva; Ustinova
Russian Journal of General Chemistry, 2006 , vol. 76, # 7 p. 1069 - 1080
反应条件
toluene bei Siedetemperatur;
参考文献
Humphlett,W.J.; Wilson,C.V.
Journal of Organic Chemistry, 1961 , vol. 26, p. 2507 - 2510
反应条件
dichloromethane; chloroform; triethylamine
参考文献
Garmaise et al.
Journal of the American Chemical Society, 1958 , vol. 80, p. 3332
