2,2,3,3,3-五氟-1-丙醇合成路线 （共 52 条）
反应条件
sodium hydride in 1,4-dioxane 1.) r.t., 2 h; 100 deg C, 20 h, 2.) 30-35 deg C, 300 psi, 40 h;
参考文献
Hung, Ming-H.; Rozen, Shlomo; Smart, Bruce E.
Journal of Organic Chemistry, 1994 , vol. 59, # 15 p. 4332 - 4335
反应条件
sodium hydroxide
T=70°C; Etherification; 8 h;
参考文献
Matuszczak, Stephen; Feast, W. James
Journal of Fluorine Chemistry, 2000 , vol. 102, # 1-2 p. 269 - 277
反应条件
1: With titanium tetrachloride
T=35°C; 0.666667 h; Inert atmosphere;
2: With zinc in diethylene glycol dimethyl ether
T=85°C; 3 h; Cooling with ice;
参考文献
E. I. DU PONT DE NEMOURS AND COMPANY; STEPANOV, Andrei, Aleksandrovich; CHERSTKOV, Victor, Filippovich; NAPPA, Mario, Joseph
Patent: WO2011/90734 A1, 2011 ;
Location in patent: Page/Page column 7 ;
反应条件
methane; nickel
T=497 - 579°C; P=822.11 Torr; Product distribution / selectivity;
参考文献
Honeywell International Inc.
Patent: US7026520 B1, 2006 ;
Location in patent: Page/Page column 3-4 ;
反应条件
methane
T=65 - 700°C; Product distribution / selectivity;
参考文献
DAIKIN INDUSTRIES, LTD.; KOMATSU, Yuzo; SUGIYAMA, Akinari; SHIBANUMA, Takashi
Patent: WO2010/87465 A1, 2010 ;
Location in patent: Page/Page column 12 ;
反应条件
hydrogen; carbon
Inert atmosphereGas phase; Product distribution / selectivity;
参考文献
DAIKIN INDUSTRIES, LTD.; KOMATSU, Yuzo; SUGIYAMA, Akinari; SHIBANUMA, Takashi
Patent: WO2010/87465 A1, 2010 ;
Location in patent: Page/Page column 12-13 ;
参考文献
Minnesota Mining and Manufacturing Company
Patent: US5157159 A1, 1992 ;
反应条件
triethylamine
T=95°C; 16 h; Yields of byproduct given;
参考文献
Heilmann, S. M.; Drtina, G. J.; Janulis, E. P.; Krepski, L. R.; Rasmussen, J. K.; et al.
Journal of Fluorine Chemistry, 1992 , vol. 59, # 3 p. 387 - 396
参考文献
Brey; Tarrant
Journal of the American Chemical Society, 1957 , vol. 79, p. 6533,6534,6536
反应条件
1-methyl-1H-imidazole in m-xylene
Heating;
参考文献
Lee, Bora; Kim, Jin Hyung; Lee, Hyunjoo; Ahn, Byoung Sung; Cheong, Minserk; Kim, Hoon Sik; Kim, Honggon
Journal of Fluorine Chemistry, 2007 , vol. 128, # 2 p. 110 - 113
