DL-1-(2-呋喃基)乙醇合成路线 （共 62 条）
参考文献
Yakugaku Zasshi, , vol. 77, p. 851,853
Chem.Abstr., , p. 1949
反应条件
hydrogenchloride 3 h; Heating;
参考文献
Kovalev, B. G.; Sorochinskaya, A. M.
Journal of Organic Chemistry USSR (English Translation), 1989 , vol. 25, # 6.1 p. 1062 - 1065
Zhurnal Organicheskoi Khimii, 1989 , vol. 25, # 6 p. 1180 - 1184
反应条件
1: N-bromosuccinmide; water; sodium acetate; sodium hydrogencarbonate / tetrahydrofuran / 1 h / 0 °C 2: 4-(N,N-dimethlyamino)pyridine / dichloromethane / 12 h / -78 - -30 °C / Inert atmosphere 3: tris(dibenzylideneacetone)dipalladium(0) chloroform complex; triphenylphosphine / tetrahydrofuran; dichloromethane / 6 h / 0 °C / Inert atmosphere 4: sodium tetrahydroborate; cerium(III) chloride / methanol; dichloromethane / 1 h / -78 °C 5: osmium(VIII) oxide; 4-methylmorpholine N-oxide / water; acetone; tert-butyl alcohol / 4 h / 0 °C View Scheme
参考文献
Wang, Hua-Yu Leo; Wu, Bulan; Zhang, Qi; Kang, Sang-Woo; Rojanasakul, Yon; O'Doherty, George A.
ACS Medicinal Chemistry Letters, 2011 , vol. 2, # 4 p. 259 - 263
反应条件
pyridine; phosphorus tribromide; pentane T=-15°C; Erwaermen des erhaltenen 5-Aethyl-furan-2-carbonitrils mit methanol. Kalilauge;
参考文献
Reichstein; Zschokke
Helvetica Chimica Acta, 1932 , vol. 15, p. 1124,1126
反应条件
1: 90 percent / NaHCO3; NaOAc*3H2O; NBS / tetrahydrofuran; H2O / 1 h / 0 °C 2: 60 percent / DMAP / CH2Cl2 / 12 h / -78 °C 3: 85 percent / PPh3 / Pd2(dba)3*CHCl3 / CH2Cl2 / 3 h / 0 °C 4: 73 percent / NaBH4 / CH2Cl2; methanol / 3 h / -78 °C 5: 96 percent / OsO4; NMO / acetone; 2-methyl-propan-2-ol; H2O / 3 h / 0 °C 6: 80 percent / H2 / Pd/C / tetrahydrofuran; ethanol / 3 h / 20 °C View Scheme
参考文献
Shan, Mingde; O'Doherty, George A.
Organic Letters, 2006 , vol. 8, # 22 p. 5149 - 5152
反应条件
magnesium sulfate in water T=160°C; 3 h; Sealed tube;
参考文献
Michalak, Karol; Wicha, Jerzy
Synlett, 2013 , vol. 24, # 11 art. no. ST-2013-D0330-L, p. 1387 - 1390
反应条件
ammonia; iodine in water T=60°C; Lieben-Haller-Bauer reaction; 2 h;
参考文献
Cao, Liping; Ding, Jiaoyang; Gao, Meng; Wang, Zihua; Li, Juan; Wu, Anxin
Organic Letters, 2009 , vol. 11, # 17 p. 3810 - 3813
反应条件
[Ru(CO)2Cl(C5Bn5)]; potassium tert-butylate; sodium carbonate in toluene
参考文献
European Journal of Organic Chemistry, , # 9 p. 1317 - 1320
反应条件
3 A molecular sieve; oxygen; sodium carbonate; Pd((-)-sparteine)2Cl2 in tert-butyl alcohol T=65°C; 24 h;
参考文献
Mandal, Sunil K.; Sigman, Matthew S.
Journal of Organic Chemistry, 2003 , vol. 68, # 19 p. 7535 - 7537
反应条件
tert-butylhypochlorite in acetic acid 1.) 25 deg C, 2 h, 2.) 90 deg C, 4 h;
参考文献
Harada, Rokuro; Iwasaki, Mariko
Agricultural and Biological Chemistry, 1983 , vol. 47, # 12 p. 2921 - 2922
