5-氯-2-氨基噻唑合成路线

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Dahlbom; Ekstrand
Svensk Kemisk Tidskrift, 1945 , vol. 57, p. 229,232
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English et al.
Journal of the American Chemical Society, 1946 , vol. 68, p. 453,457

619-33-02,2-二氯-1,1-二乙氧基乙烷+

17356-08-0

41663-73-45-氯-2-氨基噻唑

参考文献

English et al.
Journal of the American Chemical Society, 1946 , vol. 68, p. 453,457

20256-39-72-乙酸胺基-5-氯噻唑

41663-73-45-氯-2-氨基噻唑

参考文献

Pedley
Journal of the Chemical Society, 1947 , p. 431
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Paik
Ann. Rep. Res. Inst. Tuberc. Kanazawa Univ.Chem.Abstr., 1953 , vol. 11, # 2 p. 39,41
Ann. Rep. Res. Inst. Tuberc. Kanazawa Univ.Chem.Abstr., 1955 , p. 8251

41663-73-45-氯-2-氨基噻唑

16629-15-52-溴-5-氯噻唑

参考文献

BRISTOL-MYERS SQUIBB COMPANY; ZHAO, Guohua; WASHBURN, William N.; MIGNONE, James
Patent: WO2010/42674 A1, 2010 ;
Location in patent: Page/Page column 96 ;
WO 2010/042674 A1

41663-73-45-氯-2-氨基噻唑+

619-41-02-溴-4'-甲基苯乙酮

135718-54-6

参考文献

Andreani; Rambaldi; Locatelli; Isetta
European Journal of Medicinal Chemistry, 1991 , vol. 26, # 3 p. 335 - 337

41663-73-45-氯-2-氨基噻唑+

79-08-3溴乙酸

135718-53-52,6-二氯咪唑并[2,1-b][1,3]噻唑

参考文献

Andreani; Rambaldi; Locatelli; Isetta
European Journal of Medicinal Chemistry, 1991 , vol. 26, # 3 p. 335 - 337

41663-73-45-氯-2-氨基噻唑+

74370-98-2

74370-75-5

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Boehringer Ingelheim GmbH
Patent: US4259336 A1, 1981 ;

41663-73-45-氯-2-氨基噻唑+

124-41-4甲醇钠

59019-85-12-氨基-5-甲氧基噻唑

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Forlani,L. et al.
Tetrahedron Letters, 1976 , p. 201 - 202

41663-73-45-氯-2-氨基噻唑+

13176-46-04-溴乙酰乙酸乙酯

61984-76-7

参考文献

Abignente; Arena; De Caprariis; Parente
Farmaco, Edizione Scientifica, 1976 , vol. 31, # 12 p. 880 - 887