2-羟基-4-氨基苯甲酸甲酯合成路线 （共 46 条）
反应条件
1: With thionyl chloride in methanol 2: With hydrogen; palladium 10 on activated carbon in ethyl acetate
参考文献
US2004/176416 A1, ;
Page/Page column 8; 9 ;
US 20040176416 A1
反应条件
sulfuric acid T=0 - 20°C; 6 h; Reflux;
参考文献
WO2013/42135 A1, ;
Page/Page column 10; 11 ;
反应条件
hydrogen; palladium on activated charcoal in ethyl acetate
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 13, # 20 p. 3597 - 3600
反应条件
sulfuric acid in methanol
反应条件
sodium carbonate in acetone T=20°C; 24 h;
参考文献
Journal of Medicinal Chemistry, , vol. 53, # 6 p. 2482 - 2493
反应条件
sulfuric acid in methanol; water; ethyl acetate
参考文献
US2002/165218 A1, ;
US 20020165218 A1
反应条件
in diethyl ether T=25°C; 0.333333 h;
参考文献
Journal of the Indian Chemical Society, , vol. 71, # 6-8 p. 345 - 354
反应条件
methanol; sulfuric acid T=0 - 80°C; Large scale reaction;
参考文献
Organic Process Research and Development, , vol. 14, # 1 p. 92 - 98
反应条件
1: 97 percent / BBr3 / CH2Cl2 2: 95 percent / SOCl2 3: 98 percent / H2 / Pd/C / ethyl acetate View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 13, # 20 p. 3597 - 3600
