(5E)-2-疏基-5-(4-硝基亚苄基)-1,3-噻唑-4(5H)-酮合成路线 （共 8 条）
反应条件
[C4mim][OH] in water T=20°C; Knoevenagel condensation; 0.166667 h;
参考文献
Alizadeh, Abdolhamid; Khodaei, Mohammad M.; Eshghi, Ali
Canadian Journal of Chemistry, 2010 , vol. 88, # 6 p. 514 - 518
反应条件
ammonium hydroxide; ammonium chloride in methanol 0.166667 h; Heating;
参考文献
Gorizdra,T.E.; Baranov,S.N.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1968 , vol. 4, p. 52 - 56
Khimiya Geterotsiklicheskikh Soedinenii, 1968 , vol. 4, p. 67 - 72
反应条件
ammonium hydroxide; ammonium chloride in methanol 1 h; Heating;
参考文献
Gorizdra,T.E.; Baranov,S.N.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1968 , vol. 4, p. 52 - 56
Khimiya Geterotsiklicheskikh Soedinenii, 1968 , vol. 4, p. 67 - 72
参考文献
Gorizdra,T.E.; Baranov,S.N.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1968 , vol. 4, p. 52 - 56
Khimiya Geterotsiklicheskikh Soedinenii, 1968 , vol. 4, p. 67 - 72
参考文献
Ginak,A.I. et al.
Zhurnal Organicheskoi Khimii, 1970 , vol. 6, p. 1744 - 1746,1747 - 1749
反应条件
sodium hydroxide in tetrahydrofuran; acetone
Ambient temperature;
参考文献
Foye; Tovivich
Journal of Pharmaceutical Sciences, 1977 , vol. 66, # 11 p. 1607 - 1611
反应条件
1: aq. NaOH / acetone; tetrahydrofuran / Ambient temperature
2: aq. HCl / methanol / Ambient temperature
View Scheme
参考文献
Foye; Tovivich
Journal of Pharmaceutical Sciences, 1977 , vol. 66, # 11 p. 1607 - 1611
反应条件
SnCl2·2H2O in ethanol
2 h; Reflux;
参考文献
Tomasic, Tihomir; Zidar, Nace; Sink, Roman; Kovac, Andreja; Blanot, Didier; Contreras-Martel, Carlos; Dessen, Andrea; Mueller-Premru, Manica; Zega, Anamarija; Gobec, Stanislav; Kikelj, Danijel; Peterlin Masic, Lucija
Journal of Medicinal Chemistry, 2011 , vol. 54, # 13 p. 4600 - 4610
