tetrabutyl ammonium fluoride in tetrahydrofuran
T=55°C; screw cap glass vial; Product distribution / selectivity;
参考文献
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES; BEAUCAGE, Serge L.; CIESLAK, Jacek
Patent: WO2012/138530 A1, 2012 ;
Location in patent: Page/Page column 44 ;
tetrabutyl ammonium fluoride in tetrahydrofuran
T=55°C; screw cap glass vial; Product distribution / selectivity;
参考文献
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES; BEAUCAGE, Serge L.; CIESLAK, Jacek
Patent: WO2012/138530 A1, 2012 ;
Location in patent: Page/Page column 44 ;
tetrabutyl ammonium fluoride in tetrahydrofuran
T=55°C; screw cap glass vial; Product distribution / selectivity;
参考文献
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES; BEAUCAGE, Serge L.; CIESLAK, Jacek
Patent: WO2012/138530 A1, 2012 ;
Location in patent: Page/Page column 44 ;
tetrabutyl ammonium fluoride in tetrahydrofuran
T=55°C; screw cap glass vial; Product distribution / selectivity;
参考文献
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES; BEAUCAGE, Serge L.; CIESLAK, Jacek
Patent: WO2012/138530 A1, 2012 ;
Location in patent: Page/Page column 44 ;
1: With ClSO2F (sulfuryl chloride fluoride); epoxysulfonyl fluoride
T=-78°C;
2: With sodium hydrogencarbonate in water
cooling; Further stages. Title compound not separated from byproducts.;
参考文献
Laali, Kenneth K.; Okazaki, Takao; Mitchell, Reginald H.; Ayub, Khurshid; Zhang, Rui; Robinson, Stephen G.
Journal of Organic Chemistry, 2008 , vol. 73, # 2 p. 457 - 466
