5-乙酰基-噻吩-2-羧酸甲酯合成路线 (共 4 条)
反应条件
sodium carbonate in DMF (N,N-dimethyl-formamide)
T=20°C;
参考文献
BOEHRINGER INGELHEIM PHARMACEUTICALS, INC.
Patent: WO2005/79791 A1, 2005 ;
Location in patent: Page/Page column 126-127 ;
WO 2005/079791 A1
反应条件
in methanol; toluene
T=0 - 20°C;
参考文献
Millennium Pharmaceuticals, Inc.
Patent: US2011/213003 A1, 2011 ;
Location in patent: Page/Page column 64 ;
US 20110213003 A1
反应条件
bis(acetylacetonate)oxovanadium
T=175°C; 6 h; Inert atmosphereAutoclave;
参考文献
Khusnutdinov; Shchadneva; Baiguzina; Mukminov; Mayakova; Smirnov; Dzhemilev
Petroleum Chemistry, 2008 , vol. 48, # 6 p. 471 - 478
反应条件
copper(ll) bromide in ethyl acetate
6 h; Heating / reflux;
参考文献
BOEHRINGER INGELHEIM PHARMACEUTICALS, INC.
Patent: WO2005/79791 A1, 2005 ;
Location in patent: Page/Page column 126-127 ;
WO 2005/079791 A1