2-(甲氨基)-5-硝基吡啶合成路线 （共 32 条）
反应条件
in dichloromethane T=20°C;
参考文献
PFIZER LIMITED; PFIZER INC.
Patent: WO2005/28452 A1, 2005 ;
Location in patent: Page/Page column 94 ;
WO 2005/028452 A1
反应条件
methylamine in ethanol
参考文献
The Green Cross Corporation
Patent: US5371086 A1, 1994 ;
反应条件
in tetrahydrofuran; dichloromethane T=50°C;
参考文献
Bolin, David Robert; Cheung, Adrian Wai-Hing; Firooznia, Fariborz; Hamilton, Matthew Michael; Li, Shiming; McDermott, Lee Apostle; Qian, Yimin; Yun, Weiya
Patent: US2007/123504 A1, 2007 ;
Location in patent: Page/Page column 18 ;
US 20070123504 A1
反应条件
water; trifluoroacetic acid in acetonitrile T=80°C; 5 h; Sealed tube;
参考文献
Lee, Sang-Hak; Mu, Yu; Kim, Gun-Woo; Kim, Jin-Seok; Park, Seok-Hwi; Jin, Tian; Lee, Kee-Young; Ham, Won-Hun
Heterocycles, 2013 , vol. 87, # 8 p. 1749 - 1764
反应条件
potassium permanganate T=-7°C; 0.5 h;
参考文献
Szpakiewicz, Barbara; Wozniak, Marian
Advanced Synthesis and Catalysis, 1999 , vol. 341, # 1 p. 75 - 78
反应条件
sodium tetrahydroborate in tetrahydrofuran 0.333333 h; Heating;
参考文献
Katritzky, Alan R.; Rachwal, Stanislaw; Rachwal, Bogumila
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1987 , p. 805 - 810
反应条件
phosphorus trichoride in chloroform
参考文献
Talik, Tadeusz; Talic, Zofia
Journal fuer Praktische Chemie (Leipzig), 1988 , vol. 330, # 1 p. 84 - 88
反应条件
potassium permanganate T=-7°C; 0.5 h;
参考文献
Szpakiewicz, Barbara; Wozniak, Marian
Advanced Synthesis and Catalysis, 1999 , vol. 341, # 1 p. 75 - 78
反应条件
1: 74 percent 2: 79 percent / conc. H2SO4, HNO3(D=1.4) / 0.5 h / 60 - 70 °C 3: 95 percent / PCl3 / CHCl3 / 1 h / Heating 4: 92 percent / 100percent N2H4 / ethanol / Heating 5: 28 percent / CH3COOAg / 1 h / Heating View Scheme
参考文献
Talik, Tadeusz; Talic, Zofia
Journal fuer Praktische Chemie (Leipzig), 1988 , vol. 330, # 1 p. 84 - 88
反应条件
1: 79 percent / conc. H2SO4, HNO3(D=1.4) / 0.5 h / 60 - 70 °C 2: 95 percent / PCl3 / CHCl3 / 1 h / Heating 3: 92 percent / 100percent N2H4 / ethanol / Heating 4: 28 percent / CH3COOAg / 1 h / Heating View Scheme
参考文献
Talik, Tadeusz; Talic, Zofia
Journal fuer Praktische Chemie (Leipzig), 1988 , vol. 330, # 1 p. 84 - 88
