2-氰基-1-氟-4-(三氟甲基)苯合成路线 （共 5 条）
反应条件
hydrazine hydrate in butan-1-ol 4 h; Heating;
参考文献
Zhang, Xuqing; Hufnagel, Heather; Hou, Cuifen; Opas, Evan; McKenney, Sandra; Crysler, Carl; O'Neill, John; Johnson, Dana; Sui, Zhihua
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 20 p. 6042 - 6048
反应条件
in dichloromethane; butan-1-ol
参考文献
Cherney, Robert J.
Patent: US2003/216434 A1, 2003 ;
US 20030216434 A1
反应条件
in isopropyl alcohol 2 h; Reflux;
参考文献
Zhang, Xuqing; Sui, Zhihua; Lanter, James C.
Patent: US2011/306592 A1, 2011 ;
Location in patent: Page/Page column 57 ;
反应条件
formic acid; nickel monoaluminide in water
参考文献
Lipha, Lyonnaise Industrielle Pharmaceutique
Patent: US5489592 A1, 1996 ;
反应条件
potassium carbonate in N,N-dimethyl-formamide
T=80°C;
参考文献
Zhang, Xuqing; Hufnagel, Heather; Hou, Cuifen; Opas, Evan; McKenney, Sandra; Crysler, Carl; O'Neill, John; Johnson, Dana; Sui, Zhihua
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 20 p. 6042 - 6048
