1-[4-(3-溴丙氧基)-2-羟基-3-丙基苯基]-1-乙酮合成路线 （共 4 条）
反应条件
potassium carbonate; potassium iodide in acetone
Heating;
参考文献
Appleton,R.A. et al.
Journal of Medicinal Chemistry, 1977 , vol. 20, p. 371 - 379
反应条件
sodium hydroxide; tetra(n-butyl)ammonium hydrogen sulphate in dichloromethane
参考文献
G. D. Searle and Co.
Patent: US4665203 A1, 1987 ;
反应条件
potassium carbonate; sodium iodide in butanone
参考文献
G.D. Searle and Co.
Patent: EP300404 A3, 1990 ;
反应条件
1: K2CO3 / butan-2-one / 4 h / Heating
2: NaOH / methanol; tetrahydrofuran
View Scheme
参考文献
Young; Belanger; Champion; DeHaven; Denis; Ford-Hutchinson; Fortin; Frenette; Gauthier; Gillard
Journal of Medicinal Chemistry, 1986 , vol. 29, # 9 p. 1573 - 1576
