1-(2-甲基苯基)-1H-吡咯-2,5-二酮合成路线 （共 7 条）
反应条件
sodium acetate; acetic anhydride T=90 - 100°C; 0.5 h;
参考文献
Sortino; Garibotto; Cechinel Filho; Gupta; Enriz; Zacchino
Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 9 p. 2823 - 2834
反应条件
1: in N,N-dimethyl-formamide T=90°C; 0.5 h; Inert atmosphere; 2: With Ni(AC)2*H2O; acetic anhydride; triethylamine in N,N-dimethyl-formamide T=90°C; 0.5 h; Inert atmosphere;
参考文献
Canadell, Judit; Fischer, Hartmut; De With, Gijsbertus; Van Benthem, Rolf A. T. M.
Journal of Polymer Science, Part A: Polymer Chemistry, 2010 , vol. 48, # 15 p. 3456 - 3467
反应条件
1: chloroform / 1 h / 20 °C 2: sodium acetate; acetic anhydride / 2 h / Reflux View Scheme
参考文献
Yoshitake, Yasuyuki; Misaka, Junichi; Setoguchi, Koji; Abe, Masaki; Kawaji, Tomohiro; Eto, Masashi; Harano, Kazunobu
Journal of the Chemical Society. Perkin Transactions 2, 2002 , # 9 p. 1611 - 1619
反应条件
sodium acetate; acetic anhydride
参考文献
Patil, Sambhaji V.; Mahale, Keshao A.; Gosavi, Kirankumar S.; Deshmukh, Ganesh B.; Patil, Nilesh S.
Organic Preparations and Procedures International, 2013 , vol. 45, # 4 p. 314 - 320
反应条件
benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine in N,N-dimethyl-formamide T=100°C; 0.5 h;
参考文献
Kumar, Padam Praveen; Reddy, Y. Dathu; Kumari, Y. Bharathi; Devi, B. Rama; Dubey
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2014 , vol. 53, # 4 p. 392 - 398
反应条件
tetrabutylammomium bromide in neat (no solvent, solid phase) MillingGreen chemistry;
参考文献
Kumar, Padam Praveen; Rama Devi; Dubey
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2013 , vol. 52, # 8 p. 1166 - 1171
反应条件
phosphorous pentoxide 1.) 0-5 deg C 2.) RT, 4 h; Yield given. Multistep reaction;
参考文献
Balasubramaniyan, V.; Bhatia, V. G.; Wagh, S. B.
Tetrahedron, 1983 , vol. 39, # 9 p. 1475 - 1485
