2-甲基-6-氧代-1,4,5,6-四氢吡啶-3-羧酸乙酯合成路线 （共 11 条）
反应条件
1: palladium / 250 - 260 °C 2: ethanolic KOH 3: copper oxide-chromium oxide; quinoline / 315 °C View Scheme
参考文献
Ramirez; Paul
Journal of Organic Chemistry, 1954 , vol. 19, p. 183,191
反应条件
2,3-dicyano-5,6-dichloro-p-benzoquinone in 1,4-dioxane 5 h; Heating / reflux;
参考文献
ASTRAZENECA AB; ASTRAZENECA UK LIMITED
Patent: WO2006/95159 A1, 2006 ;
Location in patent: Page/Page column 60-61 ;
WO 2006/095159 A1
参考文献
Sobczak, Adam; Antkowiak, Wieslaw Z.
Synthetic Communications, 2005 , vol. 35, # 23 p. 2993 - 3001
反应条件
1: palladium / 250 - 260 °C 2: POCl3 / 130 °C View Scheme
参考文献
Ramirez; Paul
Journal of Organic Chemistry, 1954 , vol. 19, p. 183,191
反应条件
1: 30 percent Pd/C 2: Ag2CO3 / tetrahydrofuran; benzene 3: LiAlH4 / diethyl ether View Scheme
参考文献
Ruyun, Ji
Medicinal Chemistry Research, 1995 , vol. 5, # 8 p. 587 - 594
反应条件
1: 30 percent Pd/C 2: Ag2CO3 / tetrahydrofuran; benzene View Scheme
参考文献
Ruyun, Ji
Medicinal Chemistry Research, 1995 , vol. 5, # 8 p. 587 - 594
反应条件
ammonium acetate
T=80°C; Michael Addition; 5 h; Inert atmosphere;
参考文献
Senthil Kumar; Kumari, Neeta; Luthra, Pratibha Mehta
Synthetic Communications, 2013 , vol. 43, # 22 p. 3010 - 3019
参考文献
Albertson
Journal of the American Chemical Society, 1952 , vol. 74, p. 3816
反应条件
ammonia
Destillieren des Reaktionsprodukts unter vermindertem Druck;
参考文献
Emery
American Chemical Journal, 1891 , vol. 13, p. 352
反应条件
Aufbewahren; anschliessend Destillation unter vermindertem Druck;
参考文献
Emery
American Chemical Journal, 1891 , vol. 13, p. 352
