in methanol 3 h; Heating;

1: 90 percent / hydrazine hydrate / 1 h / Heating 2: 1.) 6N HCl, 2.) sodium nitrite / 1.) 0 deg C, 2.) water, 60 min View Scheme

in dimethyl sulfoxide 0.166667 h; Ambient temperature;

1: 85 percent / thiourea / ethanol / 4 h / Heating 2: 75 percent / NaOAc / ethanol / 2 h / Heating 3: 85 percent / NaOEt / ethanol / Heating 4: 65 percent / KOH / ethanol / 1 h / Heating View Scheme

hydrazine hydrate 1 h; Heating;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '2036449', constants.ctx, '0')">phosphorus pentachloride</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '956581', constants.ctx, '0')">trichlorophosphate</a> <br />T=110&deg;C;&nbsp;1.5&nbsp;h;&nbsp;<br /> &nbsp;

<b>Multi-step reaction with 3 steps<br /> </b>1: 2.) triethylamine / 1.) DMF, o deg C, 2.) DMF, 10 deg C, 4 h<br />2: 2.) sodium ditionate / 1.) methanol, 50 deg C, 2 h, 2.) ethanol, water, 50 deg C, 3 h<br />3: 1.) 35percent HCl, acetic acid, 2.) sodium nitrite / 1.) 4 deg C, 20 min, 2.) water, RT, 6 h<br /> <br /> &nbsp;