3-(3-甲氧基苯基)丙醛合成路线 （共 11 条）
反应条件
Dess-Martin periodane; trifluoroacetic acid in dichloromethane T=0 - 20°C; 20 h;
参考文献
ASTRAZENECA AB; NPS PHARMACEUTICALS, INC.
Patent: WO2005/44266 A1, 2005 ;
Location in patent: Page/Page column 14; 15 ;
WO 2005/044266 A1
反应条件
N-benzyl-N,N,N-triethylammonium chloride; palladium diacetate; sodium hydrogencarbonate in N,N-dimethyl-formamide T=40°C; Heck reaction; 24 h;
参考文献
Satyanarayana, Gedu; Maier, Martin E.
Tetrahedron, 2012 , vol. 68, # 6 p. 1745 - 1749
反应条件
[Rh(acac)2(CO)2]; hydrogen; triphenylphosphine in methanol; toluene T=65°C; P=18751.9 Torr; 0.966667 h; regioselective reaction;
参考文献
Bourne, Samuel L.; O'Brien, Matthew; Kasinathan, Sivarajan; Koos, Peter; Tolstoy, Paeivi; Hu, Dennis X.; Bates, Roderick W.; Martin, Benjamin; Schenkel, Berthold; Ley, Steven V.
ChemCatChem, 2013 , vol. 5, # 1 p. 159 - 172
反应条件
diisobutylaluminium hydride in dichloromethane T=-78°C; 0.5 h; Inert atmosphere;
参考文献
Zhu, Lili; Hong, Ran
Chinese Journal of Chemistry, 2013 , vol. 31, # 1 p. 111 - 118
反应条件
1: 84 percent / LAH / tetrahydrofuran / 20 °C 2: 60 percent / TPAP; 4 Angstroem molecular sieves / CH2Cl2 View Scheme
参考文献
Manas, Abdul Rahman Bin; Smith, Robin A. J.
Tetrahedron, 1987 , vol. 43, # 8 p. 1847 - 1856
参考文献
The Board of Trustees of the Leland Stanford Junior University
Patent: US4117234 A1, 1978 ;
反应条件
1: LiAlH4 2: PCC View Scheme
参考文献
Thuaud, Frederic; Kojima, Shuntaro; Hirai, Go; Oonuma, Kana; Tsuchiya, Ayako; Uchida, Takako; Tsuchimoto, Teruhisa; Sodeoka, Mikiko
Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 9 p. 2771 - 2782
反应条件
1: LiAlH4 2: PCC View Scheme
参考文献
Pearson, Anthony J.; Ghidu, Victor P.
Journal of Organic Chemistry, 2004 , vol. 69, # 25 p. 8975 - 8978
反应条件
1: triethylamine; palladium diacetate; tetra-(n-butyl)ammonium iodide; biphenyl-2-yl-di-tert-butyl-phosphane / N,N-dimethyl-formamide; toluene / 0.33 h / 120 °C / 11251.1 Torr 2: dicarbonylacetylacetonato rhodium (I); triphenylphosphine; hydrogen / toluene; methanol / 0.83 h / 70 °C / 18751.9 Torr View Scheme
参考文献
Bourne, Samuel L.; O'Brien, Matthew; Kasinathan, Sivarajan; Koos, Peter; Tolstoy, Paeivi; Hu, Dennis X.; Bates, Roderick W.; Martin, Benjamin; Schenkel, Berthold; Ley, Steven V.
ChemCatChem, 2013 , vol. 5, # 1 p. 159 - 172
反应条件
1: 33 percent / HCl gas / CHCl3 / 5 h 2: 74 percent / BuLi / tetrahydrofuran / 0.5 h / 0 °C 3: 59 percent / AgOTf / CH2Cl2 / 20 h / Ambient temperature View Scheme
参考文献
Manas, Abdul Rahman Bin; Smith, Robin A. J.
Tetrahedron, 1987 , vol. 43, # 8 p. 1847 - 1856
